ID A0A3B3XFW4_9TELE Unreviewed; 1577 AA.
AC A0A3B3XFW4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=FHA domain-containing protein {ECO:0000259|PROSITE:PS50006};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000013927.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000013927.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CEP170 family.
CC {ECO:0000256|ARBA:ARBA00010436}.
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DR RefSeq; XP_014831428.1; XM_014975942.1.
DR Ensembl; ENSPMET00000021793.1; ENSPMEP00000013927.1; ENSPMEG00000016311.1.
DR GeneID; 106909497; -.
DR CTD; 557463; -.
DR OrthoDB; 5489878at2759; -.
DR Proteomes; UP000261480; Unplaced.
DR Gene3D; 2.60.200.20; -; 1.
DR InterPro; IPR029300; CEP170_C.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR15715; CENTROSOMAL PROTEIN OF 170 KDA; 1.
DR PANTHER; PTHR15715:SF17; CENTROSOMAL PROTEIN OF 170 KDA; 1.
DR Pfam; PF15308; CEP170_C; 1.
DR Pfam; PF00498; FHA; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 3: Inferred from homology;
FT DOMAIN 23..73
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT REGION 116..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 368..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 539..604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 657..843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 864..1266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1314..1338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1360..1391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1501..1547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..247
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..306
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..329
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..406
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..569
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 581..604
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 698..712
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 719..760
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 775..792
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 872..901
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 929..945
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 946..961
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 963..1012
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1029..1064
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1092..1108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1126..1208
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1228..1242
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1314..1336
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1376..1391
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1577 AA; 168744 MW; 4870586265533649 CRC64;
MSVTSWFLVS SGGTRHRLPR EMIFVGRDDC ELMLQSRSVD KQHAVINYEP GTDEHKVKDL
GSLNGTFVND VRIQEQMYIT LKLEDKLRFG YDTNLFTVVR GELTVPEEAL KHEKFTSGLQ
LSKKPSSGET TANTTKSHSP CKAPTKTPKS PSGGTPKSAE SRAADGVTSS REQPTKPLDS
QKAEEKLGDS TALPRGTPLY GQPSWWGDGD ADDENSFKQE TKSKKHDGSI SESKEARRGE
KAKEDGLYAS PALDSSYFEV PTKEGHMANN GIHEIPTKDT EDAPSQSHTT AAQGHASFTI
EFDNTSPGKV TIKDHVSKFA SDHHRSRTKK STAGSGGSGS KDLTTLQAAM MASESKVADW
LAHNDPTLVH TESTEDDSKS TKSIKSDVPV HLKRLKGSKH EDGTQSDSEN GLGLRFANRR
HALEERLKTA HNHAGGGSAG ATATVSGTRA TSSRTAFMIE FYDEENPRKR RSYSFSQTAP
LLGGGVGGEG LCPQPPSHPK VFSISTSAAS AADSGKAPAP IPATVTVGAP TAARVLLKQR
SEDQSIGRSS ASTGLATGSP TTPSEDTSVL GKGAGTAGGD VDDNHSDKGT YTIELENKNP
EEEEARRMID KVFGVQENTS SLVLSDLKGK VKDSGNAGKE ALVGDSSWVS QWASLAANQA
RTDPEGSGAE AATFLHKERG SDAFESAAPP LGKGEPSSSL TDRKRRTLPQ LPVDDPRAKP
TPKALRSEIG EKQDTEPQEK ENKGDGESPT PMEDGEMTNK RKQSSATSSP SKGPVRGTER
RKRSEESNGG EAGEGGEKSG KALVRQGSFT IEKPSSNVPP ELIPRINRGN NERERSDSVG
SMDTATLLKD TEAVMAFLEA KLRDENKLDQ KSIKTPPSAS IGLAARTDSI SPESDVDTAS
TASHAAAEAG GKTAPGVVQK RKSLSSMHRE KSNMSTTSKT TSGNGSARER LERKAKGRTV
EATGRTRSAQ PGASSRARQP SLDLTDDDQT SSFPISDILS SDQETYSGPL GNSVHRRGSE
DFLHSKLDSR SSKTSMSGAS KTSRNLQAAT ASSLNKQASL PQPRPTRASL LRRARLGDTS
DTDLADADRV SVASEVSTTS STSKPPSGRK GMSRLDLLAQ PRRNRVGSVS ARSDSECTVS
RPSTASPRLS AETALRLGLR STTPTENQLS PRMRANSVSK LNEPKTKTTT SGYCSPTVSS
SSRWRRLPPE YGSTSEEEFG SSRNSAKHGA RPHVRPHHLV PHRGSRLGSA SSSGPAGVAA
IPGGAGIKHR MKEQEEYIRD WTAHSEEIAR ISQDLAKDLA ILAREIHDVA GEIDSVSSSG
TAPSTTVSTA ATTPGSAIDT REELVDRVFD ESLKFRKIPP VISSNKPPEI NGKPVEHQPR
APDGREPRAL RRRTWNREEA VLDSLLIHSV SQLSTKIRHS VDRTAGKIRI LFKDKDRNWD
EIESKLKSES EAPLLKTSNK EISSILLELK RVEKQLQVIN VMVDPDGTLD ALASLSLTSP
TKVPTAKATP PTAVSPAKES LPEILPGPDG SAASTRVQSS AASTEGREGI VGLSLARVVG
LPFSRRRPSG EEAIAQK
//
