ID   A0A3B3XG22_9TELE        Unreviewed;       634 AA.
AC   A0A3B3XG22;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=B30.2/SPRY domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000013925.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000013925.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_014864817.1; XM_015009331.1.
DR   AlphaFoldDB; A0A3B3XG22; -.
DR   STRING; 48701.ENSPMEP00000013925; -.
DR   Ensembl; ENSPMET00000021766.1; ENSPMEP00000013925.1; ENSPMEG00000016281.1.
DR   GeneID; 106931282; -.
DR   KEGG; pmei:106931282; -.
DR   CTD; 10626; -.
DR   OrthoDB; 5299679at2759; -.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   CDD; cd19839; Bbox1_TRIM16; 1.
DR   CDD; cd19769; Bbox2_TRIM16-like; 1.
DR   CDD; cd16449; RING-HC; 1.
DR   CDD; cd12890; SPRY_PRY_TRIM16; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 4.10.830.40; -; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR003879; Butyrophylin_SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR006574; PRY.
DR   InterPro; IPR003877; SPRY_dom.
DR   InterPro; IPR000315; Znf_B-box.
DR   InterPro; IPR001841; Znf_RING.
DR   PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR   PANTHER; PTHR25465:SF10; TRIPARTITE MOTIF-CONTAINING PROTEIN 16-RELATED; 1.
DR   Pfam; PF13765; PRY; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   Pfam; PF00643; zf-B_box; 1.
DR   PRINTS; PR01407; BUTYPHLNCDUF.
DR   SMART; SM00336; BBOX; 2.
DR   SMART; SM00589; PRY; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50119; ZF_BBOX; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Immunity {ECO:0000256|ARBA:ARBA00022859};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00024}.
FT   DOMAIN          19..53
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          188..228
FT                   /note="B box-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50119"
FT   DOMAIN          420..616
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
FT   REGION          53..135
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          615..634
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          275..338
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        118..135
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   634 AA;  70895 MW;  9A500A21D90A9759 CRC64;
     MAEPAAVEAA PAPKQRNLCG VCSGDLSECK PTACGHSVCD SCQGDKAKGC PKCLQSPAVK
     PAPDNGPKQN GTAAASPEKT KEEQSQDPKT VEQVKVQGKL MESEAPKAPV ESETKPEPQT
     DQGPEPEEAK EEPLGPDDVV CDSCIETPCR ALKSCLTCMV SYCEAHLRPH LENPKFQNHR
     LVEPLRDIER RTCESHKWPL ELFCCADACC ICQDCLKEEH QGHKTAPVEE ARRQIEKELS
     EKQTQMMKMV TAGDNAISKL QDNRVSIEQS VTKVRTVIES QFQELQVMVE KAKKEVTEIL
     EAEESQALKQ ADGIQVHLEQ KYTELKKAQA QTEKLSKNKN DVDFLQEYAE WKKEATDNSL
     SGIYVGLEDR LDSFSQVIQE STSNLCDMLV STYTQKVKEK CNNNEIGIKI TVQTNTAAKH
     DGSKRDPKTR ADFLQYAAQV SFDASTAHKF LRLTEENKKV TNTTPWQHPY PDVPERFENH
     RQVLAAESFY VGRHYFEVDV SGDGTHVGVT YKSIDRKGDE SSSCITGNNF SWCLQWNGRT
     YSAWHSDKET PLNVERFTRI GVYVDYSQGL LSFYGVDDTM TLLHQYQAQF LEPLYPAFFL
     PKKENIVVLV APGEPLPLKS PSPSTSPEDG PFDS
//