ID A0A3B3XH93_9TELE Unreviewed; 259 AA.
AC A0A3B3XH93;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Dickkopf N-terminal cysteine-rich domain-containing protein {ECO:0000259|Pfam:PF04706};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000014343.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000014343.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the dickkopf family.
CC {ECO:0000256|ARBA:ARBA00010842}.
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DR RefSeq; XP_014856186.1; XM_015000700.1.
DR AlphaFoldDB; A0A3B3XH93; -.
DR STRING; 48701.ENSPMEP00000014343; -.
DR Ensembl; ENSPMET00000022298.1; ENSPMEP00000014343.1; ENSPMEG00000016719.1.
DR GeneID; 106926052; -.
DR KEGG; pmei:106926052; -.
DR CTD; 100038765; -.
DR OrthoDB; 2903760at2759; -.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IEA:InterPro.
DR CDD; cd23274; Dkk3_Cys2; 1.
DR Gene3D; 2.10.80.10; Lipase, subunit A; 1.
DR InterPro; IPR006796; Dickkopf_N.
DR InterPro; IPR039863; DKK1-4.
DR InterPro; IPR047300; Dkk3_Cys2.
DR PANTHER; PTHR12113:SF8; DICKKOPF-RELATED PROTEIN 3; 1.
DR PANTHER; PTHR12113; DICKKOPF3-LIKE 3; 1.
DR Pfam; PF04706; Dickkopf_N; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..259
FT /note="Dickkopf N-terminal cysteine-rich domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017274801"
FT DOMAIN 123..173
FT /note="Dickkopf N-terminal cysteine-rich"
FT /evidence="ECO:0000259|Pfam:PF04706"
SQ SEQUENCE 259 AA; 28918 MW; 2666BBB51166A3EF CRC64;
MSGTMLLLGF WGLCLLWTAG AMERGPVSLN EMFREVEELM EDTQHMLDEA VHKITNESAK
FSSSPMDLPP SYHNETRKTV KGNNGETRIL DRTDKETDNR TGEMYTSHVQ VEVSGQWNSV
AHECIVDEDC GDLKYCLYEI ENSRCLPCIA TDMPCSKDEE CCSDQMCVWG QCTLNATQGT
AGTICQGQSD CRPGLCCAFQ REFLFPVCSP KPTKGESCLN HPNLLMDMLE WDQEGPRDHC
PCVANLHCQP HGRGSVCGE
//
