ID A0A3B3XIN7_9TELE Unreviewed; 463 AA.
AC A0A3B3XIN7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=One cut domain family member {ECO:0000256|RuleBase:RU361129};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000014892.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000014892.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the CUT homeobox family.
CC {ECO:0000256|ARBA:ARBA00008190, ECO:0000256|RuleBase:RU361129}.
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DR RefSeq; XP_014840602.1; XM_014985116.1.
DR AlphaFoldDB; A0A3B3XIN7; -.
DR STRING; 48701.ENSPMEP00000014892; -.
DR Ensembl; ENSPMET00000032779.1; ENSPMEP00000014892.1; ENSPMEG00000017349.1.
DR GeneID; 106916675; -.
DR KEGG; pmei:106916675; -.
DR CTD; 3175; -.
DR OrthoDB; 5396912at2759; -.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR003350; CUT_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR PANTHER; PTHR14057:SF9; HEPATOCYTE NUCLEAR FACTOR 6; 1.
DR PANTHER; PTHR14057; TRANSCRIPTION FACTOR ONECUT; 1.
DR Pfam; PF02376; CUT; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM01109; CUT; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS51042; CUT; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Transcription {ECO:0000256|RuleBase:RU361129};
KW Transcription regulation {ECO:0000256|RuleBase:RU361129}.
FT DOMAIN 277..363
FT /note="CUT"
FT /evidence="ECO:0000259|PROSITE:PS51042"
FT DOMAIN 383..443
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 385..444
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 24..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 102..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 235..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..123
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 463 AA; 50095 MW; 46A44E260D4D486C CRC64;
MNAQLSMENI GDLHGVSHES VAGHGELLSG HSPHSRPSPR GLGHRAMGMA TLLDSGDYHP
GHPGHLHPAI SMCEAPHGMS ASTTYTTLTP LQPLPPISTV SDKFPPHHHH HHHHPHHPHP
HPHQRLPGNV SGSFTLMRED RSLAPMNSLY PAYHHKDPCM GQSLSPLSGS GLASIHTSQA
GIPPYAHPGA AMPGEKMLTP SGFEAHHPAM LSRHAEQHMT SSAGMVQING LHHHPHAHLG
AQGHGQGLGS NREQASGPGH QGGGGGGGGG GGGGGGGVSG GQMEEVNTKE VAQRITTELK
RYSIPQAIFA QRVLCRSQGT LSDLLRNPKP WSKLKSGRET FRRMWKWLQE PEFQRMSALR
LAGERSLACK RKEQDHARSE RGNVTKKPRL VFTDVQRRTL HAIFKENKRP SKELQLTIAQ
QLGLELATVS NFFMNARRRS LDKWVDDGSG HAPNSGPNVC TKA
//
