ID A0A3B3XMT1_9TELE Unreviewed; 1148 AA.
AC A0A3B3XMT1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|SMART:SM00913};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000016265.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000016265.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
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DR RefSeq; XP_014864658.1; XM_015009172.1.
DR AlphaFoldDB; A0A3B3XMT1; -.
DR STRING; 48701.ENSPMEP00000016265; -.
DR Ensembl; ENSPMET00000024794.1; ENSPMEP00000016265.1; ENSPMEG00000018994.1.
DR GeneID; 106931195; -.
DR KEGG; pmei:106931195; -.
DR CTD; 23214; -.
DR OrthoDB; 169519at2759; -.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040016; XPO6.
DR PANTHER; PTHR21452; EXPORTIN-6; 1.
DR PANTHER; PTHR21452:SF4; EXPORTIN-6; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 31..97
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|SMART:SM00913"
FT REGION 295..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1148 AA; 130904 MW; 24D5F461CAFCDF72 CRC64;
MASDESSLRA LENLMTEFFH SCTTNERKRE IEELLNNFAQ QSGAWRHCLF FLSNTRNEYV
MMYSLTVFEN LVNKMWIGLA SQDKMEIRSC LPKLLLAQHN SVPYFIRNKL CKVIVDIGRQ
DWPMFYHDFF TNTLQLIQTP ALAPLGLVML KTTSEELACP REDLSVARKD ELRKLLLEQV
PTVLGLLTGI LETYWDKHSV IASTPPPSPT SRESVELLGS LFQGSQYSKL LCQPMAALDN
ESHQLCCLVL ECLAHLFSWI PLSTSITPTL LASIFHFARF GCDLRTKAKT GALISSTSNG
PLNPGAVPTT NGEGRNGQQS EVNKADRARI GVLAMTCVNE LVSKNCVPMD FEEYLLRMFQ
QTFFLLQRLT RENNAHTVKS RLQELDESYL EKFTDFLRLF VSVHLRRIES SPQFPIVEFL
GLLFKYTFNQ PTHEGYFACL DIWSVFLDFL TTKIKSRLAD RESVLNRYKD ALVLLLREIL
NRIQFRFNQA QLEELDDETL DDDQQTEWQR YLRQSLEVVA KVMELLPSHA FSTLFPVLQE
NLDVYLGLRQ FIVTTGSSQR LNITAENDCR RLHCSLRDLS SLLQAVGRLA EHFIGEVFAA
RFTDALAVVE RLVEVTCYGS QTGLYDLETA VPSVLKPDLT DVHAQALAAL QAYSHWLTQF
YSEVHSQNQS QFINLITSAV NASSPLITTK VPEKLLLSAS HLMVSITATV RPVFLVTLPA
VQNIFNRITT ENQSQRLPQE AHMFVCRALS NMLLLPWPNL PESEQQWQTR SNSHASLVAA
LTREYRILRG TVNISPRQPG LDNVKAVIQQ TLPVLRDIVD SISSESTKSR QICYQSLQES
VQVTLNLFPV FIQQPDVTDE MLAFFLILFQ ALRVQMGVAF TGQIIHTFLS MFTREQLAAS
ILQEGSAGCR VVQKFLKILQ VVVQEPGQAF KPFLPSILSL CMEQVYPVVA ERSSPDVKAE
MFELLYQILH QNWRYFFKTS VLTSVQKGGV DDTMENEAQF TAAMQAFGQS FLQTDIHIFK
QNLSYLESLN SKHKLYHRKL FRTSMLFHFI NVLLQVLLHK SHDLLQEEMT LAIYNMASVD
FDAFYSVFMP QFLNGCQGVD SNQRAVLARN FKLEQDLPSF TQSVQRLVND LRYYRLCNSS
LPTGTIKL
//
