ID   A0A3B3XN98_9TELE        Unreviewed;      1013 AA.
AC   A0A3B3XN98;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=SEC7 domain-containing protein {ECO:0000259|PROSITE:PS50190};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000016502.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000016502.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the BRAG family.
CC       {ECO:0000256|ARBA:ARBA00006248}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3B3XN98; -.
DR   Ensembl; ENSPMET00000033435.1; ENSPMEP00000016502.1; ENSPMEG00000019183.1.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   CDD; cd00171; Sec7; 1.
DR   Gene3D; 1.10.220.20; -; 1.
DR   Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR033742; IQSEC_PH.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR023394; Sec7_C_sf.
DR   InterPro; IPR000904; Sec7_dom.
DR   InterPro; IPR035999; Sec7_dom_sf.
DR   PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR   PANTHER; PTHR10663:SF314; IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 2; 1.
DR   Pfam; PF16453; IQ_SEC7_PH; 1.
DR   Pfam; PF01369; Sec7; 1.
DR   SMART; SM00222; Sec7; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF48425; Sec7 domain; 1.
DR   PROSITE; PS50096; IQ; 1.
DR   PROSITE; PS50190; SEC7; 1.
PE   3: Inferred from homology;
FT   DOMAIN          731..923
FT                   /note="SEC7"
FT                   /evidence="ECO:0000259|PROSITE:PS50190"
FT   REGION          1..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          121..187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          274..549
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          596..648
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          677..712
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..30
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        144..172
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        291..321
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        469..488
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        533..549
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        610..639
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        677..706
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1013 AA;  112006 MW;  0B8446FF7AF0551F CRC64;
     MMLFSEEEEE EEEEEEGGRA GRKDSVRAAE AALHRGSISG PPPARLASPR FGSGRLGSVR
     SLPPGSFRGR SAAATMWCIN CASDKTPAIL NNKLLYCVEG DPQCPEVLTF SDSSFGHPPP
     FHRYSNSPLS SPCDPYGPAS GTGPLGASHS QTQGSSPISP PSPASLAWAQ RSRHQPASLA
     LRKQEEEESK RCKALSDSYE LSTDLQDKKV EMLERKYGGQ FVSRRAARTI QAAFRRYRMN
     KKFERLRSSA SESRMTRRII LSNMRLQVKS LADSMDDSLT CQSGREDSQD VGGGEEDEDE
     EEGDEDEEEE EEEDEEEDEE VEYRQCGWRN TNTASRRAPG RAEGGRGGVA MHEDSTATSF
     SDVTLYMDDG CLPSSPLSRP ASSSDTDYWG GGGGAGGRED SRETEGGSSA SRRSSTPCTE
     CRGEYRGRGG GAGGGHLPVL TIEPPSDSSV DMSDRSERGS IGRLVYEQES SGGERDGERG
     RGGGEGESGE DELGAGSSEA ESPQGTIKHK PNGRSVAMAQ GQTRSPANVP LPMPSARTLP
     PHPLQHPHPP HPSAIPHLPT ILHHHPQYSQ HVMHMHHAHA GVPYMQHPHH FAQHHYHHLH
     HQHHHLPHSY PEPPASPLPS PVPPLTPLSP LPPPLTPSPM SSSSSSVLQN LEGQQLLAHH
     PHLHHHHHLL CSDGDNESVN STTTNSNDDT TVNNCSSGSS SRDSLREPMG GATLGKQTYQ
     RESRHSWDSP AFNNDVVQRR QYRIGLNLFN KKPEKGIQYL IEKGFVSDTP VGIARFILER
     KGLSRQMIGE FLGSRQQFNK DVLDCVLDEM DFSGMDLDEA LRKFQAQIKV QGEAQRVERL
     VEAFSQRYCV CNPVLIRQFQ NPDTIFILAF AIILLNTDMY SPNVKPERKM KLEDFIKNLR
     GVDNGQDIPR DLLVAIYGRI QKWELRTNDD HVSQVQAVER MVIGKKPVLS LPHRRLVCCC
     QLFEVPDPNR AQRSGVHQRE VFLFNDLLMV SSGNQREGKD FVVTPRKQCL AFH
//