ID   A0A3B3XQ54_9TELE        Unreviewed;       572 AA.
AC   A0A3B3XQ54;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=Protein tweety homolog {ECO:0000256|RuleBase:RU361114};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000017093.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000017093.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Probable chloride channel. {ECO:0000256|RuleBase:RU361114}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the tweety family.
CC       {ECO:0000256|ARBA:ARBA00009849, ECO:0000256|RuleBase:RU361114}.
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DR   AlphaFoldDB; A0A3B3XQ54; -.
DR   Ensembl; ENSPMET00000025868.1; ENSPMEP00000017093.1; ENSPMEG00000019944.1.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-UniRule.
DR   CDD; cd07912; Tweety_N; 1.
DR   InterPro; IPR006990; Tweety.
DR   PANTHER; PTHR12424:SF4; PROTEIN TWEETY HOMOLOG 3; 1.
DR   PANTHER; PTHR12424; TWEETY-RELATED; 1.
DR   Pfam; PF04906; Tweety; 1.
PE   3: Inferred from homology;
KW   Chloride {ECO:0000256|RuleBase:RU361114};
KW   Chloride channel {ECO:0000256|RuleBase:RU361114};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Ion channel {ECO:0000256|RuleBase:RU361114};
KW   Ion transport {ECO:0000256|RuleBase:RU361114};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361114}.
FT   REGION          444..463
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          510..572
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        444..461
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   572 AA;  63265 MW;  F83321BBA880A191 CRC64;
     MKHSLDNHNF QTKERNSACL CISLLSYVAC LWICFLPLSV NRLPAFFIHI LNAPLPSGKD
     QCGTSILLIG AMAVLCLGLD LIFLLIYSFW LCCRRCKKED SSHSHSHSQQ PSADCCCTAW
     CVIIATLVCS AGIAVGFYGN GESSDGASRL AYSLRHANRT VSGVEKLVSD NTLALNQTVE
     ENLAQLETTF QDQTDYVAII QKLQGQLDEL VRLMVDVPFW SNTDISLEDL AQKTEAFDFY
     RWLGYLGLLL FDVLICLLVL FGLIRNSRGT LIGYVCFLGV LTLIISWGSL GLELGVSASD
     FCVSPDSYIT SVTKDNAVIN QDILQYYLRC SSGKVNPFQQ RLSGSHKALV EMQDDVAELL
     RSATRDYATE NLEQIQSVLN STEVGLHQLT ALVDCRSLHM DYVQALTGLC YDGVEGLIYL
     VLFSFVTALM FSSIVCSVPH TWPRKRMDDE DGEDESGASR GVHDNLYRVH MPSLYSCGSS
     YGSEASLPAT AHTVSNAPVT EYMSQNANFQ NPRCENTPLI GRESPPPSYT SSMRAKYLAT
     NRPEQNRRSV PNDQLDPSSR PNPAARPQSS VH
//