ID A0A3B3XTK2_9TELE Unreviewed; 809 AA.
AC A0A3B3XTK2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B {ECO:0008006|Google:ProtNLM};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000018409.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000018409.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the semaphorin family.
CC {ECO:0000256|ARBA:ARBA00009492}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR RefSeq; XP_014863527.1; XM_015008041.1.
DR STRING; 48701.ENSPMEP00000033041; -.
DR Ensembl; ENSPMET00000027506.1; ENSPMEP00000018409.1; ENSPMEG00000021336.1.
DR Ensembl; ENSPMET00000027526.1; ENSPMEP00000033041.1; ENSPMEG00000021336.1.
DR GeneID; 106930471; -.
DR CTD; 7869; -.
DR OrthoDB; 5342713at2759; -.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0007411; P:axon guidance; IEA:UniProt.
DR CDD; cd05871; Ig_Sema3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF37; SEMAPHORIN-3B; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00022989}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..809
FT /note="Sema domain, immunoglobulin domain (Ig), short basic
FT domain, secreted, (semaphorin) 3B"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040590458"
FT DOMAIN 54..537
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT DOMAIN 586..695
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 32..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 691..711
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..809
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 789..809
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 809 AA; 91684 MW; E1D5FA54023749D0 CRC64;
MMTMMMMMMV TCSSLLVLGM AAAYSSSSSV TRASSSSSSS SSSSSSPTSS SSPRMKLSYK
ELQQYHGVRR FELERSCCFS AMLLDEERGR LFVGAKNFLL SLSLDNIAKQ EHKIYWPAPV
DWREECNWAG KDITSDCVNY VKIVHHYNRT HLYACGTGAF HPTCAFVEVG HRMEDHVFRI
DPSKVEDGKG KSPYDPRHNA ATVLIGDELY AGVATDLMGR DFTIFRSLGK RPSIRTEQHD
SRWLNEPKFV GSFWVPESEN PDDDKIFFFF RETAVEAQGL GKSTYSRIGQ LCRNDMGGQR
SLVNKWTTFL KTRLICSVPG ADGSDTYFDE LRDVFLLQTR DKKNPLVYTV FSTSSSVFKG
SAVCLYSMND IRRAFLGPFA HKEGPNYQWV PFQGKVPYPR PGMCPSKTFG SFESTKGFPD
DVIQFARHHP LMYNPVYPMN RRPVFVRTNV EYSFTQIAVD RVNAADGQYD VMFIGTDKGT
VLKVISVPKE SWNNMEELLL EELEVFKDAS SVINMQISSK RQQLYVGSDT GIAQVPLHRC
SVYGKACAEC CLARDPYCAW DGTSCTRYLP NTKRRFRRQD VRNGDPNTLC SGDHHKHRVA
ERKLYGVEGS STFLECIPKS LQARVTWTYQ KQPQNPREEV RLDERILQTD RGLLIRRVLK
RDVGVYQCHA MEHGFTQTLL GITLEVVPST SSSISNLPSD SPVRLDPRSG GAPSLTNQKL
WYRDFMQLVD HPNLSTVDQI CEQVWARKHA GADQVSKSFE SPRKEIVPLG PAVRPANKKW
KHLQEIRKGR NRRTHDGKPS SRAPRSARE
//
