ID   A0A3B3XU81_9TELE        Unreviewed;       477 AA.
AC   A0A3B3XU81;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Arf-GAP domain-containing protein {ECO:0000259|PROSITE:PS50115};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000018460.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000018460.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_014838444.1; XM_014982958.1.
DR   AlphaFoldDB; A0A3B3XU81; -.
DR   STRING; 48701.ENSPMEP00000018460; -.
DR   Ensembl; ENSPMET00000027585.1; ENSPMEP00000018460.1; ENSPMEG00000021390.1.
DR   GeneID; 106915386; -.
DR   KEGG; pmei:106915386; -.
DR   CTD; 64744; -.
DR   OrthoDB; 1022106at2759; -.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   CDD; cd08859; ArfGap_SMAP2; 1.
DR   Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR   InterPro; IPR037278; ARFGAP/RecO.
DR   InterPro; IPR001164; ArfGAP_dom.
DR   InterPro; IPR038508; ArfGAP_dom_sf.
DR   PANTHER; PTHR45705; FI20236P1; 1.
DR   PANTHER; PTHR45705:SF4; STROMAL MEMBRANE-ASSOCIATED PROTEIN 2; 1.
DR   Pfam; PF01412; ArfGap; 1.
DR   PRINTS; PR00405; REVINTRACTNG.
DR   SMART; SM00105; ArfGap; 1.
DR   SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR   PROSITE; PS50115; ARFGAP; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT   DOMAIN          13..137
FT                   /note="Arf-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50115"
FT   REGION          171..204
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          216..237
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          452..477
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        186..204
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        452..470
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   477 AA;  51287 MW;  98E8533EDD221709 CRC64;
     MTGKSVKDVD RYQTVLNSLL ALEENKYCAD CESKGPRWAS WNLGIFVCIR CAGIHRNLGV
     HISKVKSVNL DQWTQEQVQC VQEMGNAKAK RLYEAFLPEC FQRPETDQAA EIFIRDKYEK
     KKYMDKVIDI QMLRKEKSCD NIPKEPVVFE KMKLKKDVSP KTDSQAVTDL LGLDAPTPSP
     AVSNGGGCVP DSNESPAASN PAQAQSALDL FGSLPAPTSV SSTKTMPASG SLPQSRVTAS
     VPENLSLFMD PKPKAEEGAV KKLSKDSILS LYASTPSLHA SGMATHGLYM NRMGFPTHPY
     GPYHSLAQVG GMGGAMMTSQ MAMMGQQQSG LMGVHQNSMI GAQQNCMMGQ QNGLMGAQGV
     MAQPSGVVAT PYMTGMGQGM MGQQQSGMVL QQQNGALAAQ QSGMMGQQQV GGMAPLPHQQ
     MYGVQQGQQL QWNMAQMTQQ VAGMNLYSTN GMAGNGSQHT GSSTAPSSAH MTAHVWK
//