ID A0A3B3XXV9_9TELE Unreviewed; 437 AA.
AC A0A3B3XXV9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=TGF-beta family profile domain-containing protein {ECO:0000259|PROSITE:PS51362};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000019881.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000019881.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR RefSeq; XP_014837128.1; XM_014981642.1.
DR AlphaFoldDB; A0A3B3XXV9; -.
DR STRING; 48701.ENSPMEP00000019881; -.
DR Ensembl; ENSPMET00000029379.1; ENSPMEP00000019881.1; ENSPMEG00000022917.1.
DR GeneID; 106914684; -.
DR KEGG; pmei:106914684; -.
DR CTD; 9210; -.
DR OrthoDB; 5301288at2759; -.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR PANTHER; PTHR11848:SF22; BONE MORPHOGENETIC PROTEIN 15; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 326..437
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 38..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 437 AA; 49508 MW; 60D4347944B46BA8 CRC64;
MRATRAKHGF LRVCVLTCFI YLLCSTCTGV LTGRKMASRQ LAPRRSRRSH RGAHHRPLTD
EQKADQNLQF MLSLYRSAAE PDGRPKQHRK FGSNTVRLLR PAESSVHYLP ASGDLTYTFT
VQYKVDTLPS EQLVRASFVH LRTSSTPSGT TQAVEPPLCR AQITSLGASS LVTLEPHQRW
TETDITAHVS AHISQEKDQG EQGHLTLIAQ YWCAEPADRD ASPSWWWTPL WGRRGLSGEP
QLEVPSLLLY LEEEREVKEW MGDLLGAEGE NLMRRVGWWE QPTIRRRRSS KEAKDSSLDE
LKDALASSLS SSTSSTASIF SDISNFKRKT EVPKNRCKLH SFNLAFNELG LGHYFIAPRA
YNPRYCQGDC PRVLHYGYHS PNHAIIQTLI KELGVGDVPP PSCVPYKYMP MSVLVVYKKK
VDYRELEDMV AESCTCR
//
