ID   A0A3B3XY64_9TELE        Unreviewed;       459 AA.
AC   A0A3B3XY64;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=IRF tryptophan pentad repeat domain-containing protein {ECO:0000259|PROSITE:PS51507};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000020022.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000020022.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3XY64; -.
DR   Ensembl; ENSPMET00000029549.1; ENSPMEP00000020022.1; ENSPMEG00000023819.1.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:UniProt.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR   CDD; cd00103; IRF; 1.
DR   Gene3D; 2.60.200.10; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR019817; Interferon_reg_fac_CS.
DR   InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR   InterPro; IPR019471; Interferon_reg_factor-3.
DR   InterPro; IPR017855; SMAD-like_dom_sf.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR   PANTHER; PTHR11949:SF9; INTERFERON REGULATORY FACTOR 6; 1.
DR   Pfam; PF00605; IRF; 1.
DR   Pfam; PF10401; IRF-3; 1.
DR   PRINTS; PR00267; INTFRNREGFCT.
DR   SMART; SM00348; IRF; 1.
DR   SMART; SM01243; IRF-3; 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00601; IRF_1; 1.
DR   PROSITE; PS51507; IRF_2; 1.
PE   4: Predicted;
FT   DOMAIN          7..115
FT                   /note="IRF tryptophan pentad repeat"
FT                   /evidence="ECO:0000259|PROSITE:PS51507"
SQ   SEQUENCE   459 AA;  51678 MW;  620753057E68B30E CRC64;
     MAVTSRRVRL KPWLVAQVDS ARYPGLVWVD REAMRFRIPW KHATRHTPQH EDEDTIFKAW
     AVETGKFQEG VDEPDPPKWK AQLRCALNKS REFKLVYDGT KEVPMNPLKV YDVCDIPQPN
     NAGSHTPYGE DFGEDPTPDS LCPNPSNGDC TSPSPLMWSL MGSHPSIQPP SCPPSNEVWP
     IEEPADVKMP PTNMDELPPA PLPDSILQPA PLSDVFASPE MWISSLPMTD LEVQFLYRGK
     EVSPTVTVSN PLGCRLFYGE LGPILNQEEL FGPVNLAQLR FPTTEHITND KQRVFTNRLL
     DVMDRGLILE IRGHDIYAVR LCQCRVYWSG PCAPNPAAPN LIERQKVVKL FCLESFLSGV
     VAQQRGQATS PPQFEISLCF GEEYPDGRPK ERKLIMVQVI PVVARMINEM FSGDNNLSFD
     SSSVRLQISI PDIKDNIVSH LKELYSLLQN HQGQEGGWL
//