ID A0A3B3XZQ9_9TELE Unreviewed; 1460 AA.
AC A0A3B3XZQ9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=RUN and SH3 domain containing 2 {ECO:0008006|Google:ProtNLM};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000020592.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000020592.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSPMET00000030274.1; ENSPMEP00000020592.1; ENSPMEG00000023732.1.
DR Proteomes; UP000261480; Unplaced.
DR CDD; cd17702; RUN_RUSC2; 1.
DR Gene3D; 1.20.58.900; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR InterPro; IPR047342; RUN_RUSC2.
DR InterPro; IPR047343; RUSC1_2.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15591:SF14; AP-4 COMPLEX ACCESSORY SUBUNIT RUSC2; 1.
DR PANTHER; PTHR15591; RUN AND SH3 DOMAIN CONTAINING; 1.
DR Pfam; PF02759; RUN; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00593; RUN; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF140741; RUN domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50826; RUN; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 966..1110
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT DOMAIN 1389..1448
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 33..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 72..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 227..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 324..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 445..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 554..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 626..655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 763..816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 849..881
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1152..1201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1227..1341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1362..1381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..113
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..153
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..344
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..478
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..503
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 640..655
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 700..716
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 790..808
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1181..1201
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1227..1241
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1285..1299
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1300..1324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1460 AA; 156740 MW; CC078964BED947A5 CRC64;
MDSPPKVSGE TLIVHHIPLM HCQVSGGCGG SLKRTNPFSP PESLGLSRTT SLPERDVLQR
EALLYSSLIQ TSSGSWSSSG GVGREKRGGG GRGGSTASDD SSFTSSNSED LLITAHTLPR
AKPRNRNPLR RNPFLLNTDE DEDEEDEDDS DNLHGYLEDS SFHLHSKTNA ALDDAMAPFL
GFASEPFLLH GSGEGSSRES LRGASSDLSN HLDDLDVLGL DRECRHGSSG SNVSMDCGEH
DWVDDDEEED DDQPMRCGQS SKTGSYSSGS SNQHCSCCAL SQNFPETFAE PFLDFQQGYC
SDSSCNSSEG VLVNFSAIYN KMNNGIPEKQ PPPAGTSSVS DLHGNQQDAI GGGAFYLDLH
TSPTEPPPSC FSNAFPLIRE PRLSSSSACS CSMEHQATLD LDANCNSFHP PHAAGSSGDL
ASCLQSQARL VVATQNYYKL VTCDLSSQSS PSPAGSSVNS CSSEHSKGSP TPSQPSEYFL
FRQRGEEQGL EEEEDKDGAS SRRDDDDDDD DEDDENEEKT KKNGGQQDAE AAGVAPSVIE
GQVYVNISPP MAQRSVIGGS GAPSGGRPRS RSYDRNLDRC PSPRLGSLER MLSCPMRLSD
GAAQAATPPP PPPPRVTSFA EIARSKRRHG GAGGSPSTKA AADPFSSTYS THSHSSVDFS
PILEQRVESV SPAALPVRFT RCYSQGSIER HLEGVKESQT KTEGVLSSSS ESPPAVVRYS
KDQRPTTLPI QPFTFHHQFT SKPPQPKPLL PLLTGYVSGM QARPCSGSGS GSGGPVGEES
EEAAEIGHGY QSSRSATAPP TESVRPSPLG SYSPVRLQGA LSSGSCSTCT PSPKPAHSLS
CPLSAGLGSL HTPPAGRQGN GSVPLAHTPP PPSLGVKRGV VPPTLPAVQG QCLHHNGPAL
HTDTLSPLGC LDSGKLSDRG KGSGSRTQNG LVKAVNTAVD LIVAHFGTSR DPDVKAKLGN
SWVSPNVGHL ILKYLCPALR NLLQDGLKAY VLDLIIGQRR CQPWSVVEAS TQLGPSTRVL
HSLFSKVSQF SELTSHSMRL NAFVFGLLNM KSLEFWFNHL YTHEDIIVAH YSPGGFLPLS
QGPCKPLFEE LLLLLQPLSL LPFDLDLLFE PHLLQKGQEQ LRRKEQLRSA GPASRSTFQL
MRGWSTTVGD VARSERPGLR REGTWPGMER DGATAGASLW KERAKDVKER DRRKEKDPGH
KQAGWWYQLM QSSQVYIDQS AEGSKFVKAE KRKKSSERRQ NQPPPAREGV VEGAESEGER
GASGGESRGR PSWMGSPPES ILNREKDPNL AEDTGVEIRD ESPSQGQSLR WGRLFGSTVG
SPQRAESAEL RARAQKTRPP SGWLSLDRSI LDLVAVTIGA GGAKKAEPPT TPTHGQTTVP
LPLTETKQSS SCEVRALCHH LATDPGQLSF NKGDVLRVLR KADPDWLLCS LGSTRGLVPI
IYVTLSSMED SRSETGLSQL
//
