ID   A0A3B3Y0W0_9TELE        Unreviewed;       334 AA.
AC   A0A3B3Y0W0;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=Chimerin 1 {ECO:0008006|Google:ProtNLM};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000020760.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000020760.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_014853646.1; XM_014998160.1.
DR   AlphaFoldDB; A0A3B3Y0W0; -.
DR   STRING; 48701.ENSPMEP00000020760; -.
DR   Ensembl; ENSPMET00000030461.1; ENSPMEP00000020760.1; ENSPMEG00000023974.1.
DR   GeneID; 106924453; -.
DR   KEGG; pmei:106924453; -.
DR   CTD; 1123; -.
DR   OrthoDB; 5395569at2759; -.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0048468; P:cell development; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.30.60.20; -; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR046349; C1-like_sf.
DR   InterPro; IPR020454; DAG/PE-bd.
DR   InterPro; IPR002219; PE/DAG-bd.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR46075; CHIMERIN FAMILY MEMBER; 1.
DR   PANTHER; PTHR46075:SF6; N-CHIMAERIN; 1.
DR   Pfam; PF00130; C1_1; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   PRINTS; PR00008; DAGPEDOMAIN.
DR   SMART; SM00109; C1; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
DR   PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR   PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          80..130
FT                   /note="Phorbol-ester/DAG-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50081"
FT   DOMAIN          143..334
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   334 AA;  38001 MW;  2E572CEDDAAEBDEA CRC64;
     MPSRESYDVQ KKDKPLVQKA KREANQEDIL AAALGMRMGP QKPSATFWQP LKLLAYSQLT
     SLVRRASLKE VVQSPRSEKV HNFKVHTFRG PHWCEHCARF MWGLMAQGVK CADCGMNVHK
     ECSAQVPNDC KPDLRHVRKV YSCDLTTLVK AYNTARPMVV DMCIREIESR GLKSEGLYRI
     SGFSDSVEEV KSGFDKDGEK TDISVNAYED INIITSALKL YLRDLPVPVI SYDAYPMFIE
     ATKLTDPEKK LEAFREALAL LPPSHKETLK YLMAHLKRVT QNEKFNLMSA ENLGIVFGPT
     LMRAPNQDAM TALNDIRYQR QVVEVLIKNE DVLF
//