ID   A0A3B3Y6M1_9TELE        Unreviewed;       453 AA.
AC   A0A3B3Y6M1;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=SET domain-containing protein {ECO:0000259|PROSITE:PS50280};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000023001.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000023001.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_014830635.1; XM_014975149.1.
DR   RefSeq; XP_014830637.1; XM_014975151.1.
DR   AlphaFoldDB; A0A3B3Y6M1; -.
DR   STRING; 48701.ENSPMEP00000023001; -.
DR   Ensembl; ENSPMET00000011301.1; ENSPMEP00000023001.1; ENSPMEG00000004255.1.
DR   GeneID; 106908897; -.
DR   KEGG; pmei:106908897; -.
DR   CTD; 54093; -.
DR   OrthoDB; 11215at2759; -.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd19177; SET_SETD4; 1.
DR   Gene3D; 3.90.1420.10; Rubisco LSMT, substrate-binding domain; 1.
DR   Gene3D; 3.90.1410.10; set domain protein methyltransferase, domain 1; 1.
DR   InterPro; IPR015353; Rubisco_LSMT_subst-bd.
DR   InterPro; IPR036464; Rubisco_LSMT_subst-bd_sf.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   InterPro; IPR016852; SET_MeTrfase.
DR   InterPro; IPR044429; SETD4_SET.
DR   PANTHER; PTHR13271:SF163; SET DOMAIN-CONTAINING PROTEIN 4; 1.
DR   PANTHER; PTHR13271; UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE; 1.
DR   Pfam; PF09273; Rubis-subs-bind; 1.
DR   Pfam; PF00856; SET; 1.
DR   PIRSF; PIRSF027158; Lys_MTase_YDR198C_prd; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          49..273
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..21
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   453 AA;  51720 MW;  99BFA20E7CE2FC9A CRC64;
     MKGRSRRVGR TARKRKRKRE QSVHSVSLSH QLQYVRLMKF LHQRGFSSTL LQPALFSDTG
     RGLKTLQTIM PGELVVSLPE SCLLTTSTVL SSYLGEYIKS WKPRLSPLSA LCVFLVCERQ
     RGEASDWFPY IDVLPYSYAC PTYFSEEVAD VLPAGVRRRG LEQREAVREM HSSNQEFFRT
     LQPVLSQPIE DVLTYEALRW AWCSVNTRSV FMSRPSSCFL SGPDSYALAP FLDLLNHHPD
     VQVKAGFNDQ TKCYEIRSVC GTPCYEQVFI NYGSHDNQRL LLEYGFVAMN NPHSVVYVEP
     DLLCDILRGE KSLDQKMKFL RENNFLENLT VSSEGPSWRL MVALRLLSLP QTLYHLWRPA
     LLGQVVDEKT EVRSSQTART LCQQLLKDTH IALDKISQLL GQCGGPVREQ LEVVRALRQE
     ERWILENCVT ALRDSVILEK ETSSCKANIG VMS
//