ID   A0A3B3Y7D8_9TELE        Unreviewed;       303 AA.
AC   A0A3B3Y7D8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=MARVEL domain-containing protein {ECO:0000259|PROSITE:PS51225};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000023281.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000023281.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the synaptophysin/synaptobrevin family.
CC       {ECO:0000256|ARBA:ARBA00006476}.
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DR   RefSeq; XP_014843611.1; XM_014988125.1.
DR   AlphaFoldDB; A0A3B3Y7D8; -.
DR   STRING; 48701.ENSPMEP00000023281; -.
DR   Ensembl; ENSPMET00000010612.1; ENSPMEP00000023281.1; ENSPMEG00000005144.1.
DR   GeneID; 106918409; -.
DR   KEGG; pmei:106918409; -.
DR   CTD; 368919; -.
DR   OrthoDB; 2881347at2759; -.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008021; C:synaptic vesicle; IEA:InterPro.
DR   InterPro; IPR008253; Marvel.
DR   InterPro; IPR001285; Synaptophysin/porin.
DR   PANTHER; PTHR10306; SYNAPTOPHYSIN; 1.
DR   PANTHER; PTHR10306:SF16; SYNAPTOPORIN; 1.
DR   Pfam; PF01284; MARVEL; 1.
DR   PRINTS; PR00220; SYNAPTOPHYSN.
DR   PROSITE; PS51225; MARVEL; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|PROSITE-ProRule:PRU00581, ECO:0000256|SAM:Phobius};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00581,
KW   ECO:0000256|SAM:Phobius}; Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..303
FT                   /note="MARVEL domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017430782"
FT   TRANSMEM        81..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        115..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..202
FT                   /note="MARVEL"
FT                   /evidence="ECO:0000259|PROSITE:PS51225"
FT   REGION          227..246
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   303 AA;  34655 MW;  8EEA63DB97B15268 CRC64;
     MCMVIFAPIF AICAFATCGG YHGYLQVKVD CSARRPNNLS INIEFGYPFR LQQIHFKAPL
     CDASREEVIF LNGDFSAAAQ FFVTVGVLAF LYSFFATIVY VFYQNKYLKN NRGPLVDFLV
     TVTFSLMWLL SSCCWAKSLT DIKAATNPTE VLLLIASCRE KENRCATTQE PFWSRLNTST
     VFGFLNAILW SGNIWFVFKE TGWYKTGQRY PSRTSSRKRS SEMRERLYSE SSFDQPDDGF
     GPFRQDSFTE SRGNYDKQLE RQASINQSQV NFSLPETYLG KAVIYERENK VASQGPAIFV
     NEM
//