ID A0A3B3Y820_9TELE Unreviewed; 2616 AA.
AC A0A3B3Y820;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Otogelin {ECO:0008006|Google:ProtNLM};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000023506.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000023506.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00039}.
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DR STRING; 48701.ENSPMEP00000023506; -.
DR Ensembl; ENSPMET00000009984.1; ENSPMEP00000023506.1; ENSPMEG00000005292.1.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0046556; F:alpha-L-arabinofuranosidase activity; IEA:InterPro.
DR GO; GO:0046373; P:L-arabinose metabolic process; IEA:InterPro.
DR CDD; cd19941; TIL; 5.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR InterPro; IPR007934; AbfB_ABD.
DR InterPro; IPR036195; AbfB_ABD_sf.
DR InterPro; IPR006207; Cys_knot_C.
DR InterPro; IPR036084; Ser_inhib-like_sf.
DR InterPro; IPR002919; TIL_dom.
DR InterPro; IPR014853; VWF/SSPO/ZAN-like_Cys-rich_dom.
DR InterPro; IPR001007; VWF_dom.
DR InterPro; IPR001846; VWF_type-D.
DR PANTHER; PTHR11339; EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED; 1.
DR PANTHER; PTHR11339:SF228; OTOGELIN; 1.
DR Pfam; PF05270; AbfB; 1.
DR Pfam; PF08742; C8; 4.
DR Pfam; PF01826; TIL; 2.
DR Pfam; PF00094; VWD; 3.
DR SMART; SM00832; C8; 4.
DR SMART; SM00041; CT; 1.
DR SMART; SM00215; VWC_out; 1.
DR SMART; SM00216; VWD; 4.
DR SUPFAM; SSF110221; AbfB domain; 1.
DR SUPFAM; SSF57603; FnI-like domain; 1.
DR SUPFAM; SSF57567; Serine protease inhibitors; 4.
DR PROSITE; PS01225; CTCK_2; 1.
DR PROSITE; PS51233; VWFD; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00039}; Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 36..214
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 388..564
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 814..983
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 1801..2010
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 2531..2616
FT /note="CTCK"
FT /evidence="ECO:0000259|PROSITE:PS01225"
FT REGION 1294..1342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1398..1540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1576..1606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1622..1655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1668..1687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1713..1798
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1398..1461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1472..1503
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1512..1540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1622..1654
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 2545..2594
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00039"
SQ SEQUENCE 2616 AA; 286223 MW; E17F5A8F0BDCE729 CRC64;
LNGGQCYLTE SCDCSLFQAT GHRCQTVPNL GFEREMTCRT WGQYNFETFD GLYFHFPGRC
TYTLLRDCEE TTQGSIVVQV HNDPNCGSAP YACQRSVSLF LPWDGEIQLH ATSVTFKGQS
LQLPHHIHEL HLEQISQYVL VTQQQGFTLA WEGRSGSVYI KLSPEFVGRT CGLCGNFNAD
IQDDLKTSYG VLTPDVEMFG NSWMEMEPHQ DRCPHVPSAF QSPCAGKVEE VCAVLLDPPF
QSCHDFVSPL SYMASCSNDL CMSGPSGDVV CQVFSEYARA CAHADHPLHN WRQLKQCPLG
LQYRECISCC PETCNLERTC IDSKLACLDG CYCPEGLIYE EGSCVAPADC PCEYHGMFYP
SGQTLQEECN NCTCVGGVWN CTDHTCPGEC SVTGDMYFQS FDGRIFTFPA TCQYVLAKSR
NSGKFAVTIQ NAPCGANLDG ACIQSVNLVI DEDPRTEITL SHVGEVFMAG QYRVSLPYSD
DIFHIQELSS MFLQVRTAFG LHLQYSWTEF RLYLQADETW KDDTVGLCGT FNGNTQDDFL
SPSGMIESTP HLFGNAWKVS SACSLSLSSP PLDPCDTHQQ AVTYASEMCD ILNQDLFAAC
HEYLSPTPFH LQCRADTCRC GTPCLCSALA HYARHCRRFS IIVDFRAHVS DCAVTCPATM
QYGTCVSACQ RRCSSLSVPQ HCGGDCEEGC VCPQGSFYNH RTHTCVHRLC PPGQLHLNCS
DGENSQSAGR GVACERTCES YLLNITCSAH EPCVAGCACP PGLLKHGDEC FEPDACPCLW
KGKEYFPGDR VSSPCYQCVC QHGMFQCVFR PCPSMCTTYG DRHYRTFDGL LFDYVGACKV
YLVKSSADVM LSVLVENVDC FDSGIICRKS LLINIRGSFI SFDDDSGKPN PSSVIDRKQQ
MFIWPAGYFT IIHFPEEDVT VLWDRKTTVH VQVGPRWQGK LSGLCGNFDL KTINEMRTPD
NIDSPTPQEF GNSWTAMECV NSPDIRHPCS LSPLREPFAK HQCGVLLSEV FQTCHPVVDV
TWFYMNCLAD TCACSRGGDC ECFCTSVAAY AGRCCHEGVP VDWRSPSLCR KEKPPRLVRV
NTSADAAPGI LSEFMMTPGL SRARPHDASR VSFEAVDRPN YFLHASASGQ VRLAKWEGSD
AFWDGATFVL HRNTWISGYD SLESHAKPGF FLHATPPRLH LLKFRHSYGF RKASLFRLTD
TPPGPRCQWR YDSCINPCFR TCSDPSADSC VTIPQVEGCL PVCPQNTVLD EITRRCVHVE
DCKGRTTVSS TATTSYKAAP VEGMTTAPFI LPELPTTSST TASPVSTSPT KEAGTGYSST
ASTEPFQPVS SFTTSKATQT GTTERTLHII PTDRTTSSTV YVSSTTTVYH VKPSTTPPSA
FTSATTRWQT STLKKVTESS ASEISTVSTT TASPKPLTSR PLVVPETSTM STDVQFTTKP
STGITTLQQS PTTQSTTHPL HTERTSEPRY PPHWEVTSTS TTTYQPPLET TPGLPSESPT
MSAKSPEVPP LPVTSRTAST SAASTTTTET SAPESGATTT RKLITPPVAL FTSTTRGPRP
SSLHTTLKPI IETSKPVTTR VSTTTTSMSS PSLHSLHTTT STTAPEVSTV LEKVTTRLVS
SSRATPTAVR TSTLSATPRL PATSRVTSRA TSPAVRPITA RVTVATRPSA TTTTSTVVGS
PATTSPTIAT TASRVGHVAT LAAISHLTTT APLASPSSTA AFTRESTTTK EAETTTSPSR
PDVFVSTQEP GIPVPTTTHQ ESTTAFQNIS TSPGSTTVSS SPRTTAAPTS SSVERLTSMS
ETPIVDECTK YICVNNQLIL FNKSQSCPFT AEPPNCGLLG FAVLVNGDKC CPKWDCPCRC
SMFPDLNVIT FDGDSFAIFK AASYIVAQLP NETLSVLIQE CPADSDRPLF VNSRYAKPRF
KKYGFEIYDT GNMYLIRSPA GLKVQWYHST GMMVIDADDA GSKLPTMGLC GFCDGDLTND
LTLPNGSVLG VSQDPVLFID SWQVPNTTSY VSYSRRREHN CSTSDCSRCL AMLEDNAFTP
CHAFVPPSTF CEVWVRDSEY VNNHCVALAA YVAICHKFSV CIEWRRPDYC PFVCPGSLSY
QACLPACTSQ SCPNHDFDSD PDHCSGLTEG CVCPEGTLLH RPYSALCISP EKCACTDSGG
VPRSHGEVWK ASQDGCCMYR CDNDTIVPVE YDCSSAPAPV CHRTGEMIIS MSDDTSCCPH
KVCVCNQTLC DRFPPECKYG EKLVSYFRPE SCCPDYVCEC DPERCESELP ACRDDQTPVA
TRADGSCCLA HICMCSSCVE RPPSCRDGEV LSVDSNSTDR CCPSYQCVCE PYRCPQLTCP
VGMSVMSVSS PDLCCPNQTC GMIPTRCCSK QYSVFAAVCV FGERGLLQPG QTLVEHGDDG
LCYSRHCSQV LDPASGFYLL RISTVNCSAH CHPNQIYVPP KDQSTCCGEC KNISCIYQHE
NGTVGLYKPG RSWVSNCKKF DCSDTSFGPT LISYSYSCPP FNETECMKIG GTVVSYMDGC
CKTCKEDGKS CQKVTVRMTI RKNDCRSNRP VNIVSCDGKC PSASIYNYNI NTYARFCKCC
RETGLQRRSV QLYCSSNATW VSYSIQEPTD CSCQWS
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