ID A0A3B3YAR0_9TELE Unreviewed; 1360 AA.
AC A0A3B3YAR0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=DNA repair protein REV1 {ECO:0000256|ARBA:ARBA00020399};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000024165.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000024165.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
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DR RefSeq; XP_014860966.1; XM_015005480.1.
DR RefSeq; XP_014860967.1; XM_015005481.1.
DR RefSeq; XP_014860968.1; XM_015005482.1.
DR RefSeq; XP_014860969.1; XM_015005483.1.
DR STRING; 48701.ENSPMEP00000024165; -.
DR Ensembl; ENSPMET00000008370.1; ENSPMEP00000024165.1; ENSPMEG00000006226.1.
DR GeneID; 106928905; -.
DR KEGG; pmei:106928905; -.
DR CTD; 51455; -.
DR OrthoDB; 169741at2759; -.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR GO; GO:0042276; P:error-prone translesion synthesis; IEA:InterPro.
DR CDD; cd17719; BRCT_Rev1; 1.
DR CDD; cd01701; PolY_Rev1; 1.
DR CDD; cd12145; Rev1_C; 1.
DR CDD; cd19318; Rev1_UBM2; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 6.10.250.1630; -; 2.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR Gene3D; 1.20.58.1280; DNA repair protein Rev1, C-terminal domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR025527; HUWE1/Rev1_UBM.
DR InterPro; IPR012112; REV1.
DR InterPro; IPR031991; Rev1_C.
DR InterPro; IPR038401; Rev1_C_sf.
DR InterPro; IPR047346; Rev1_UBM1/2.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR45990; DNA REPAIR PROTEIN REV1; 1.
DR PANTHER; PTHR45990:SF1; DNA REPAIR PROTEIN REV1; 1.
DR Pfam; PF16589; BRCT_2; 1.
DR Pfam; PF00817; IMS; 2.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF21704; POLH-Rev1_HhH; 1.
DR Pfam; PF16727; REV1_C; 1.
DR Pfam; PF14377; UBM; 2.
DR PIRSF; PIRSF036573; REV1; 2.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA synthesis {ECO:0000256|ARBA:ARBA00022634};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 50..137
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 562..802
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 158..484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 618..644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 996..1050
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1084..1106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1201..1250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..197
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..244
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..284
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 377..413
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 996..1022
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1360 AA; 148844 MW; FCC34B36B32ACACD CRC64;
MSRDGWMRKR ANGSDDNGWG EKGGYMAAKV TKLDEQFKLN ASREKQKEGT GSSIFSGVSI
YVNGYTDPSA DELRRLMMVH GGQFHVYYSR SKTTHIIANN LPNCKIQELR GEKVIRPEWI
TDSIKAGRLL PCFKYQLYAK QKNTLFPAVI LRHTSEMSEP SHCPLQPSTH QKPLLPPHNT
EPSVPRSGGS SNNPFPVPGC SEAEPQSVRR SSKASLDCHP QSHLKSSQLV SGSLHTSRSL
HKNPLPNKGH SKLPHKSPGS AHVNDEDLKI NGVLQTSPDT SSHSKMTEMQ ERGDPCPVGA
SAAVGEAPLT NGHAHLFNGA LKPEGSSPVA DPRSSDGDAS TCRAKSSTEK PQSSSVQSHA
KPDPYEFPPS PPKQSDSLLI CLEQSTTQDG GLCDPKPPSS SSHEASRANE PQTPLKRLQP
PAQVEPISEQ TSRPPPSCSL SSVRLNGSRH KAFQTDAPLP NAARVAAKPD PPTEAPSAST
PSDQLLEQTG GLISEFYSHS RLHQISTWRI AFSEYVNELH SKRKTEGSPS YPGKERLRKC
MAQRSTHGQA GAPSVGSVKS CIFHVDMDCF FVSVGIRHRP ELKGKPVAVT SNRGLGKVPI
RPGANHQVEL QYYQMRHTHP QPDKADDDLP VTPSQDIPDS HGNGVDPDAA TLSMAEIASC
SYEARQAGVR NGMFFGKAKQ LCPSLQSVPY DFDAYKEVAL NMYEILASYT HDIEALSCDE
ALIDASHLLA EVGVTPDALA EAIRADIRGK TGCCASVGMG SNILLARLAT RKAKPNGQYF
LRSEEVDDFI RDLPVTSLPG VGHVMAKKLA VMGVKSCGDL QQVSLSQLQK KFGPRTGQTL
FRFCRGLDDR PVRFEKERKS VSAEMNYNIR FATVDEAECF LTNLSMEVQR RLKEAGLRGR
RVTLKVMVRK VGAPLEPAKY GGHGICDNLA KTVMLAQSTD SGQLIASAII RLLHAMKLQV
QDLRGVGIQV QQLEGNQPQA QDCRGTRTRS IKDMLLGQGS NARTTNKAGS PQKQTSSAAA
LSSPHPPTPP EPVPGTSKDT PVCRAAQKHS RTRLNLSIEV PSPSQVDRSV LEALPAELRE
QVEQSWTKRD ERPNHCRSPD LQLSSPHPAP YAPPAGTLVL QFPNQPDSPG IVLELPNFSQ
VDPDVFAALP KELQDELKSA YSRAHNVQPQ VKMAEQKNPL LQLKQPAAGT GVGRLKRRYK
RKNGVSPVKK GTSPLKRRQA TNSPAKRVPP IKPQEPANVP KTEMNPSTSE QDVVVSVTKS
WPRPVPTLAG ACDLTDIKTL LREWVTTITE PMEEDILQVV KYCTDLIEDK DLEKLDLIIR
YMKRLMQQSV ESVWSMAFDF ILDNIQVVVH QAYGSILKIT
//
