ID   A0A3B3YBB0_9TELE        Unreviewed;       819 AA.
AC   A0A3B3YBB0;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000024641.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000024641.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3B3YBB0; -.
DR   STRING; 48701.ENSPMEP00000024641; -.
DR   Ensembl; ENSPMET00000007108.1; ENSPMEP00000024641.1; ENSPMEG00000007099.1.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   CDD; cd15287; 7tmC_TAS1R2a-like; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR   InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR   InterPro; IPR017979; GPCR_3_CS.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR   PANTHER; PTHR24061:SF441; TASTE RECEPTOR TYPE 1 MEMBER 2B-RELATED; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF07562; NCD3G; 1.
DR   PRINTS; PR00592; CASENSINGR.
DR   PRINTS; PR00248; GPCRMGR.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   SUPFAM; SSF57586; TNF receptor-like; 1.
DR   PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170}; Signal {ECO:0000256|SAM:SignalP};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..819
FT                   /note="G-protein coupled receptors family 3 profile domain-
FT                   containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017394671"
FT   TRANSMEM        547..572
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        584..603
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        615..640
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        660..680
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        711..728
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        740..762
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        768..788
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          546..810
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
SQ   SEQUENCE   819 AA;  92585 MW;  05F0076A35671949 CRC64;
     MCTKRVLAIL CLLGGFLHHL NEAVTSSEFR LDGDYLIGGL FDIHLASKVL NGDRPETITC
     SSHPFILTSY RRLQIMRFST EQINNSTNLL PGVTLGYEIF DHCSDTKNFP GIFKLISADG
     IVQPWDQSNV NVSKVIAVVG TYTSTETLTV APLFMTNLIP MVTYAAASSV LSEKTYFPSF
     LRTVHPNKHI IEVFFYILQK FNWRWVSFLY TDGDYGKDGL DLFQNMIKDT EICLAYTKSL
     DENTDYPPMF QQLESQRVNV IIAFTLEWTA EDLIKGAIKH NFTNKVWIAG DGWSLHQKLR
     REKGIRKIGT VLGVAEPVIT IPGFSDFIHS SKTLCQTENP EQGRFCNQIS NCNNLTAEDV
     INADPSFSFS VYAAVYSIAK ALHAVLQCGD GRCNRTIPVK PHMVLAALRK SNFTLLNQRI
     QFDKNGDPKF GSYSIFYWNQ IGETEEVGVY HFESFFHINR TKIQWHGNGE VPSSFCSKEC
     PAGFSKTQEG IYKCCFNCTI CPSGTYINTT EDPYNCISCK ETEWSDPGST LCRLRLVEFI
     PFTDSGAIVI VMGTCTLMGL TVAISVLFAI NYHTPVVRSA GGPMCFLILG CLALCSLSVF
     FYFDKPTSAS CVFRFLPFLL FFTVCLAGFV VRSFQIVCIF KIAAKFPKLL SWWMKYHGQW
     LVISVAFVTQ AVLLLISYSI TPPKPYSDRL LYLDKTILGC DIDLKSMSGP VIFLSLLCCL
     CFIFSYMAKD LPKNYNEAKS ITFCLMLLIL TWIIFATSSI LYRGKYVSSF NALAVLSSLY
     SFLVWYFFPK CYIIMFHPNK NTQQHFQCLI QNYTKTISQ
//