ID   A0A3B3YC71_9TELE        Unreviewed;       549 AA.
AC   A0A3B3YC71;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=SHC (Src homology 2 domain containing) transforming protein 2 {ECO:0008006|Google:ProtNLM};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000024946.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000024946.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3YC71; -.
DR   STRING; 48701.ENSPMEP00000024946; -.
DR   Ensembl; ENSPMET00000006303.1; ENSPMEP00000024946.1; ENSPMEG00000007632.1.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd01209; PTB_Shc; 1.
DR   CDD; cd09925; SH2_SHC; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 3.30.505.10; SH2 domain; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR006019; PID_Shc-like.
DR   InterPro; IPR006020; PTB/PI_dom.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR035676; SHC_SH2.
DR   PANTHER; PTHR10337; SHC TRANSFORMING PROTEIN; 1.
DR   PANTHER; PTHR10337:SF5; SHC-TRANSFORMING PROTEIN 2; 1.
DR   Pfam; PF00640; PID; 1.
DR   Pfam; PF00017; SH2; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   PRINTS; PR00629; SHCPIDOMAIN.
DR   SMART; SM00462; PTB; 1.
DR   SMART; SM00252; SH2; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF55550; SH2 domain; 1.
DR   PROSITE; PS01179; PID; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   4: Predicted;
KW   SH2 domain {ECO:0000256|ARBA:ARBA00022999, ECO:0000256|PROSITE-
KW   ProRule:PRU00191}.
FT   DOMAIN          121..267
FT                   /note="PID"
FT                   /evidence="ECO:0000259|PROSITE:PS01179"
FT   DOMAIN          454..545
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   REGION          32..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          426..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   549 AA;  59519 MW;  1789E392E50D7C3A CRC64;
     SGSSPGSAAP PEATTTFCML IPKMPQWKFS NSLLSRSPSS SSSSKDSTKT ASSSSLSNRT
     SGASPASGPV ASLAAVLNSC DPVCVTPCPA GHGFGVAAEV MGSFIHKPSQ GWLHPDKKIV
     GQGASYIVRY MGCIEVLKSM RSLDFNTRTQ VTREAINRLC EAVPGGKGAW RKKTLNKALQ
     SVMGKSNLRF AGMNIALNIS VDGLGLLVPT TRQDTPDYVA YVAKDPVNQR ACHILECSDG
     LAQSVISTIG QAFELQFKQY LHSPPKTMPI RTEEPVWGED EDASEHDYYN SIPGKEPPVG
     GVVDSRLRPT GALLGHIHTQ PQSKTATQTT CGSGETPYGY LCADGQPPGS KDYEEHQYVN
     TQSLENLESF THGADGHKGA RPHDSPKKDL FDMRPFEDAL KLHEACGGAV GSGVLVGSGS
     QVGGVRNLED QWPSPPRRRA PVAPNEEQLR RETWYHSRMS RRDAEKLLVR DGDFLVREST
     TNPGQYVLTG MHCGLPKHLL LVDPEGVVRT KDMLFESISH LIAYHLKNEL PIVAAESELH
     LKQAVRRKQ
//