ID A0A3B3YFI8_9TELE Unreviewed; 1043 AA.
AC A0A3B3YFI8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=GTPase activating Rap/RanGAP domain like 3 {ECO:0008006|Google:ProtNLM};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000026126.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000026126.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3YFI8; -.
DR STRING; 48701.ENSPMEP00000026126; -.
DR Ensembl; ENSPMET00000003355.1; ENSPMEP00000026126.1; ENSPMEG00000009806.1.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR001180; CNH_dom.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR PANTHER; PTHR15711:SF62; GTPASE-ACTIVATING RAP_RAN-GAP DOMAIN-LIKE PROTEIN 3; 1.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00780; CNH; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SMART; SM00036; CNH; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50219; CNH; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468}.
FT DOMAIN 199..415
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT DOMAIN 497..814
FT /note="CNH"
FT /evidence="ECO:0000259|PROSITE:PS50219"
FT REGION 821..848
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 948..993
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 821..844
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 959..982
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1043 AA; 116742 MW; D82BB1C4303D0EEA CRC64;
MNSDKNAYLG KDKGIMRKRA LLLRKGCSFE ITSSASEDLG CRRGDFSRKH YGSVELLISS
DADGAIHRAG RFRVENGSLD EASDYTPGTW RRTDVHLENP EYHTRWYFKY FLGKVHQNYV
GTDAEKNPFY LSVVLSDQNN QRVPQYRAIL WRKTGTLKIS LPYSPTKTLS VKSILSAMNM
DRFEKGPREI LNPEIQKDLL VLEEQEGSVN FKFGVLFARD GQLTDDEMFS NETGSENFDK
FLNLLGDTVT LQGWAGYRGG LDTKNDTTGL QSIYTVYQGH ELMFHVSTML PYSKENKQQV
ERKRHIGNDI VTIVFQEGDD ASSSFKPSMI RSHFTHIFAL VRYNSQNDSY RLKIFSEESV
PLFGPPLPSP PVFTDHHEFR DFLLVKLING EKATLETPTF AQKRQRTLDM LIRSLYQDLM
PDLHKNMLNR RSFSDVLPES PKSARKKEEA RQAEFVRIGQ ALKLKTIVRG DAPTSLVTTG
LCRKEPWESQ SFCSTFPYEI ICADSWGQSL LVATDTAGVL MLDGPDPPLP GAETPTLPPV
QVFDKTMAVK QMHILEPQDL LITRADKGKD ARLYVFRLGG IKRGLEERQL VRSKCDCREN
KLEKTKGCHL YSINTHHGSE LRIVAAIRTK LLLITRKHPR FSAVATGADS PVEEFQYIRE
ICLCDPPVVM ALVDGPTGEN DNMICVAYKH QFDLINESTG DAYRLHHVDA NRVNFVAAID
VYEDGEAGLL LCYNYICYYK KVCPFNGSTP MIQSNTSDFQ FSWNQMPNAI VCAFPYILAF
TTDSIEIRLV VNGNLVYTAV VPELQLAASR SDIYFVSSAP VSSASNCSSR DTSSQSSPQT
PTGYEMPVFP SPLGDDSIRI PYGTKLSLYM SKDAEGEATC KQIFKIPLCN LVGRSIERPL
KSPLVNKVMT APAPAMMAST PLISATHSLS LSRMEIKEIA SRTRKELLGL TEEPSGKSDS
GSVKQRKMSK KNTDEDPKAR ALTSTNSDRL ASDSVDAELD VQLHCSSALE ADPEMVVLQE
GSPPLASAFA LSTSFEDDVL DLK
//
