ID A0A3B3YH68_9TELE Unreviewed; 1190 AA.
AC A0A3B3YH68;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPMEP00000026711.1};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000026711.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000026711.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cell cortex
CC {ECO:0000256|ARBA:ARBA00004544}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR AlphaFoldDB; A0A3B3YH68; -.
DR STRING; 48701.ENSPMEP00000026711; -.
DR Ensembl; ENSPMET00000001852.1; ENSPMEP00000026711.1; ENSPMEG00000010656.1.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd01381; MYSc_Myo7; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 2.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR036106; MYSc_Myo7.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR46049; AGAP003327-PA; 1.
DR PANTHER; PTHR46049:SF5; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 3; 1.
DR Pfam; PF00612; IQ; 4.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 4.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00139; MyTH4; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50096; IQ; 4.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51016; MYTH4; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}.
FT DOMAIN 65..741
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1019..1190
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT REGION 618..640
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 906..937
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 158..165
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1190 AA; 138336 MW; 6E4098757DAFB628 CRC64;
LIFLMQGDYV WLDLKTGREF DVPVGAVVKL CDSGQIQVLD DEGREHWIFP QNATNIKPMH
PTSIHGVEDM IRLGDLNEAG ILRNLLIRYN EHVIYTYTGS ILVAVNPYQL LPIYTPDQIR
LYTNRKIGEM PPHIFAIADN CYFNMQRNNK DQCCIISGES GAGKTESTKL ILQFLAAISG
QHSWIEQQVL EATPILEAFG NAKTIRNDNS SRFGKYIDIH FNKRGAIEGA KIEQYLLEKS
RVCRQAADER NYHIFYCMLK GMGPEMKAKL GLGLARDYCY LTAGNCTECD GRDDLADYSS
ILSAMKVLMF SETEYVEISK LLAAILHMGN LRFEARTYDN LDACVVVRSP DLVTAASLME
VEPKDVMVCL TTRTLITRGE SVTTPLSVEQ GLDVRDAFVK GIYGRLFVWI VDKINAAIYR
PPSCESSVIR RSIGLLDIFG FENFLVNSFE QLCINFANEN LQQFFVRHVF KLEQEEYNLE
DINWQHIEFT DNQEALDMIA NKPMNIISLI DEESKFPKGT DATMLYKLNS QHKLNTNYIP
PKNSYETQFG IQHFAGVVHY ESRGFLEKNR DSLHTDIIQL VHSSKNKFIK QIFQADVAMG
VETRKRSPTL SSQFKRSLEM LMRTLSVCQP FFVRCIKPNE FKKPMLFDRE LCIRQLRYSG
MMETIRIRRA GYPIRYSFAE FVDRYRVLMR GIKPSHIQDD LKGTCQQIVS ARLGKQEDWQ
IGKTKIFLKD HHDMQLEIER DKAITDKVIL IQKSVRGLKV RSNFRRLRSA VVFIQKVWRG
YRSRKNYQIM KSGFIRLQAV CRSRKYYRSY RITRCRITLI QARCRGFLVR QTFWRRLRAV
LTLQAYTRGM IVRRLCQRLR AERQRRLEAE RQRLAEEEQL RNQMTVRRAK AEAERKHQER
LFQLAQQQEE REREAKEEAR RKKELLDQME REKEQPVDHS DMVDRMFGFL GDSGPLPNQD
GQAPAGFEDL EQTPRGEEAE EEMLNEALPL PDEEEEDLSD YKFSKFAATY FQGLSTHTYI
RRPLKQPLLF HEDEGDQLAA LAVWITVLRF MGDLPEPKCQ IVINDGSEKI PVMTKIYETL
GKRTYKRELQ ELQVEEEVRQ YSQKRNSVRH KLVSLTLKRK SKITEEVTRR LTEGVDYSLQ
GNSMLEDRPT SNLEKLHFII GNGILRPTLR FAEHIQSLSG VDNQLQFGRH
//
