ID   A0A3B3YHR4_9TELE        Unreviewed;       613 AA.
AC   A0A3B3YHR4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000026585.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000026585.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3YHR4; -.
DR   STRING; 48701.ENSPMEP00000026585; -.
DR   Ensembl; ENSPMET00000002194.1; ENSPMEP00000026585.1; ENSPMEG00000010350.1.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SMART; SM01288; FISNA; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
FT   DOMAIN          136..268
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   613 AA;  70975 MW;  4065DB508CE8A2E9 CRC64;
     MLSFFGISYR FRHIVRKIFS FVIEVHTQTL LRISEMVLFS SFFSSDFDVR CQQELKEHLK
     KKLQRLSEGV AEPGNQTFLN QIYTELHITE GLTREVNQEH EVRRIETASR KQETAIRRED
     IFKPGRDQPI SDQPIRTVMT MGVAGIGKTL LTQKFTLDWA EGRTNQDIDF IFPFTFRELN
     MLKEDHFSLV GLIHERFTKT KGISNFEMFK VLFIFDGLDE SRLPLDFHKT KMLTDPEKST
     SVDVLLTNLI RGKLLPSALL WITTRPAAAN QIPAECVGMV TEVRGFTDPQ KEEYFRKRFR
     DDEEKASRII SHIKTSKTLY IMCHIPVFCW ITAKVLEDVM ETREGGELPS TLTEMYIEFL
     LVQNKIKEEK YDGQQKTKSI WSPENRKLID SLGSLALDQL LKGNLIFYDK DLKRCGIDIT
     DAALFSGVFT EMFKKERGTR NISVYSFVHL SIQEFLAAVY MLHCFTSRRS EKVMEKSLSS
     ENGHLDLFVR FLHGLTVESN QRLLEDLLGQ TENSPETIQS IITNLKEMNT DGISTDRRIN
     IFYCLVEMND VSFYQIQRLL DSGKQLSGTD CSALAFMLQM SEVLDELDLE KYNTSMDGRQ
     RLVPAVRNCR KAR
//