ID   A0A3B3YM63_9TELE        Unreviewed;       387 AA.
AC   A0A3B3YM63;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Pre-mRNA-splicing regulator WTAP {ECO:0000256|ARBA:ARBA00017540};
DE   AltName: Full=Female-lethal(2)D homolog {ECO:0000256|ARBA:ARBA00033097};
DE   AltName: Full=WT1-associated protein {ECO:0000256|ARBA:ARBA00032703};
DE   AltName: Full=Wilms tumor 1-associating protein {ECO:0000256|ARBA:ARBA00032336};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000028441.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000028441.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the fl(2)d family.
CC       {ECO:0000256|ARBA:ARBA00010313}.
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DR   AlphaFoldDB; A0A3B3YM63; -.
DR   Ensembl; ENSPMET00000018593.1; ENSPMEP00000028441.1; ENSPMEG00000013570.1.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0080009; P:mRNA methylation; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IEA:InterPro.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   InterPro; IPR033757; WTAP.
DR   PANTHER; PTHR15217:SF0; PRE-MRNA-SPLICING REGULATOR WTAP; 1.
DR   PANTHER; PTHR15217; WILMS' TUMOR 1-ASSOCIATING PROTEIN; 1.
DR   Pfam; PF17098; Wtap; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW   mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT   REGION          220..387
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          107..134
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        220..272
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        287..307
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        325..348
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        368..387
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   387 AA;  42549 MW;  8680655F03D3DB21 CRC64;
     MTNEEPLPKK VSTVPWKQHD AYVQVLETKY AELCSNDVPG LKESEEKLKQ QQQESARREN
     ILVMRLATKE QEMQECTTQI QYLKQVQQPS VAQLRSSMVD PAINLFFLKM KAELEQTKDK
     LEQAQNELSA WKFTPDSQTG KKLMAKCRML IQENQELGRQ LSQGRIAQLE AELALQKKYS
     EELKSSQDEL NDFIIQLDEE VEGMQSTILV LQQQLKESRQ QLTQSQGASA GPGPSRTSPS
     TSSKDYGRVS NGPSNSNSSQ RSETTTPSLY REVSSAEEDF PMSPVVSSPG DTETKLPNHS
     EEVPGSQTAS GRVGGPAGFR SQLSAGYESV DSPTGSETSL TQHSNDTDST TDPNEDKAAL
     VTKGARTAGS RHAQNGLDSN TSDGAVL
//