ID A0A3B3YRT6_9TELE Unreviewed; 1208 AA.
AC A0A3B3YRT6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=C2H2-type domain-containing protein {ECO:0000259|PROSITE:PS50157};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000030166.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000030166.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the sal C2H2-type zinc-finger protein family.
CC {ECO:0000256|ARBA:ARBA00038474}.
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DR RefSeq; XP_014852960.1; XM_014997474.1.
DR AlphaFoldDB; A0A3B3YRT6; -.
DR STRING; 48701.ENSPMEP00000030166; -.
DR Ensembl; ENSPMET00000021900.1; ENSPMEP00000030166.1; ENSPMEG00000016395.1.
DR GeneID; 106924008; -.
DR KEGG; pmei:106924008; -.
DR OrthoDB; 4271981at2759; -.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 4.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23233; SAL-LIKE PROTEIN; 1.
DR PANTHER; PTHR23233:SF85; SI:CH211-212K18.5; 1.
DR Pfam; PF00096; zf-C2H2; 2.
DR Pfam; PF13894; zf-C2H2_4; 1.
DR Pfam; PF12874; zf-met; 1.
DR SMART; SM00355; ZnF_C2H2; 6.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 3.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 6.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 6.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 387..414
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 415..442
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 748..775
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 776..803
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 809..836
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1120..1144
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 237..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 287..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 341..384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 453..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 541..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 604..697
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 834..862
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 890..928
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 941..1208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..60
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..382
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 625..639
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 640..697
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 987..1015
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1056..1070
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1081..1095
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1193..1208
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1208 AA; 126184 MW; 7B2669F489D5E12C CRC64;
MSRRKQKRPQ QLVNSDPGGP KLLQDDHLSL KSPSTSLGSD LTSSGSSSSS PTSLQDCQPP
LATRPSPGGL HAPSLPSESS PPPHWPSHIA PFTTSLPNTH SSLSPDFPHP SLSSQTHSPP
PLDQSSGTHS LNHQVNTLSV MTSPPMGSSA TTTTSSSSSS SSAQQPQPDS SSPGQQQSST
SSGEQGQIQV PQTLAVLLEE LRVLQQRQIH QMQITEEICR HVLRLGGAVF GQDNNAQASG
ADCNQKSTGT ASSSPTHPST NTPVTTASSL LSGLPSSLFP QPAISKSGTS LINGDRSQSS
STSSSFSSSS LAISSSINSS VASLHPLSLS LGLSPRYLHE KSSNTSSFGH SNGISFQTPS
LPTTSHSQDI QSSSSLISAS PSGRPQHVCR FCGKVLSSDS SLQIHLRSHT GERPYQCPVC
LSRFTTRGNL KAHFLRHREQ NPELSLSLLP PALSEQTQSG SAPGSVQRRR KRRADDDEAY
NGVKGSVPSI TESMALGLLS GGSTRPSPSS LPLPPSVDMA LLSTAHSLLQ LNRASAAVSS
TSSTALPSSS PSSSSTSSQY KGAKQQRFDE NTPPHSTLHT TSPYSQLAHL PKILFPGGAS
PHHLALLRPP GHPSTSHLSL SHQLPFPFPP FPKPPTSSPS SSSPTTSTQT SDTSKLQRLV
QKLEKQPQGT ASSCPSASSP STSSQTSADV NGDTNVRDLT TTSSAYRREM LAALGLSPSV
SAAVTGQGVS GSGPTTTTSA LPTAPIANQC GVCMRVLSCP RALRLHQATH LGERPFPCKL
CGRSFSTKGS LRAHLATHRA RPPNARALNS CPLCPRKFTN ALVLQHHIRL HLGGQIPPDE
EIPPDDGAET EGATFKDSHG EPISSLSKVQ ILPLALTTGS KSPVDALCSG SSFKQSKATD
SDSVKNEELE RSTPSVSPPL SCNPPSAGAD KTLQLAVIAS AESPTEEKTQ TDLGSASPFK
APLPSSHSVV DKIESVSDDT PLSLCVSKPG VDNTTPRLVN SDVQRSPNER ALSPSHTADP
PSVDPVPSLS PPTSPGATLE AEETGSGVKQ ELRGRNTSSS KGKRDATTSR EPLPMSEPEL
GKEAPVKEDS AALKKLSDNP ETPAGASTPH AQPARPDKPY SCSHCGKAYA SRSGLKGHMK
MHPGVLMTTP SKAQTNESDP TEDRGTSNKI SAQQEEKQGL APEKGDSADL LPTSGGSAVT
TDTMDTTT
//
