ID   A0A3B3YSE4_9TELE        Unreviewed;       351 AA.
AC   A0A3B3YSE4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=SH3 domain containing GRB2 like 1, endophilin A2 {ECO:0008006|Google:ProtNLM};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000030088.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000030088.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC       Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC   -!- SIMILARITY: Belongs to the endophilin family.
CC       {ECO:0000256|ARBA:ARBA00006697}.
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DR   RefSeq; XP_014856200.1; XM_015000714.1.
DR   AlphaFoldDB; A0A3B3YSE4; -.
DR   STRING; 48701.ENSPMEP00000030088; -.
DR   Ensembl; ENSPMET00000021755.1; ENSPMEP00000030088.1; ENSPMEG00000016291.1.
DR   GeneID; 106926060; -.
DR   KEGG; pmei:106926060; -.
DR   OrthoDB; 25371at2759; -.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd07613; BAR_Endophilin_A1; 1.
DR   CDD; cd11803; SH3_Endophilin_A; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR004148; BAR_dom.
DR   InterPro; IPR035824; Endophilin_A_SH3.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR14167:SF50; ENDOPHILIN-A1; 1.
DR   PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR   Pfam; PF03114; BAR; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   PRINTS; PR01887; SPECTRNALPHA.
DR   SMART; SM00721; BAR; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS51021; BAR; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   3: Inferred from homology;
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          18..249
FT                   /note="BAR"
FT                   /evidence="ECO:0000259|PROSITE:PS51021"
FT   DOMAIN          289..348
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          264..288
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   351 AA;  39565 MW;  689474B3ADF7D97D CRC64;
     MSVAGLKKQF HKATQKVSEK VGGAEGTKLD DDFKEMEKKV DITSRAVLDI MTKTTEYLQP
     NPASRAKLSM INTMSKIRGQ EKGPGYPQAE SILGDAMLKF GRDLGEESCF GLALIDAGEA
     MKELGEVKDA LDMEVKQNFI DPLQNLHDKD LKEIQHHLKK MEGRRLDFDY KKKRQGKVQD
     DEIKQALEKF DESKEIAEQS MFNLLESDIE QVSQLAALVQ AQLEYHSRSS EILQQLSSKM
     EDRIKEVSSK PRKEYTPKPK MTLELLPPSE SHNGGIHSAK SPGKSPAPMD QPCCRALYDF
     EPENEGELGF KEGDIITLTN QIDENWYEGM INGQSGFFPI NYVDILVPLP H
//