ID A0A3B3YXB6_9TELE Unreviewed; 961 AA.
AC A0A3B3YXB6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Bromodomain and PHD finger containing, 3a {ECO:0008006|Google:ProtNLM};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000031660.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000031660.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3B3YXB6; -.
DR Ensembl; ENSPMET00000024826.1; ENSPMEP00000031660.1; ENSPMEG00000018975.1.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15572; PHD_BRPF; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR019542; Enhancer_polycomb-like_N.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF133; BROMODOMAIN AND PHD FINGER-CONTAINING PROTEIN 3 ISOFORM X1; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF10513; EPL1; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00249; PHD; 2.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 234..284
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 288..409
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 606..676
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 832..915
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 79..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 409..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 780..817
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 542..588
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 79..94
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..450
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 961 AA; 108948 MW; D238A2D766A0BD16 CRC64;
MGRGRGRGRG RGRQAGQPRP PSPYRLQLSP SRETLTYAQA QKIVEVDLDG RLHRINITDP
LPVITEDEMM AQDIAECNSN KENSEQMQGK NRSWRKPNNK SRRSGKNTSQ QNQRSGSQQQ
TGSSCSFQHP SHQSPLPEPT FRELGSVSPC EAPPLPAAYY RYIEKSGEEQ DNVAEYDMDE
EDLAWLEMVN QKRVCDGHAS VSPDTFELLI DRLERESVLE SRSQALSQNA VDEDAFCCVC
LDDECLNSNV ILFCDICNLA VHQECYGVPY VPEGQWLCRC CLQSPSRPVD CVLCPNRGGA
FKQTSDGRWA HVVCAIWIPE VCFANTVFLE PVEGVKNIPP ARWKLTCYLC KQKGRGASIQ
CHKANCYRAF HVTCAQKAGL FMKIDPVRET GVNGTTFSVK KTAFCENHSP VGSRRDASGD
ESVEGRLVGG RGSRGQRSYT QSPPSPTNKK PTKGQKKKNT KGSGSTRRSN VPVLLVPQIP
SHRLNKICTG VEVQRKNQFM QRLHNYWLLK RQSRNGMPLI RRLHSHLQTH KAAEQKEPDE
KLSAAREELR YWQKLRQDLE RARLLVELIR KRERLKREQM KIQQAALELS LTPAQVLLKS
TLDQLQEKDS AKIFSQPVNL SEVPDYLEFI SEPMDFSTMR SKLEGHAYCS IGDLEKDFEL
MISNCLKYNS KDTLFHKTAL QLREVGGAVL RHAQRQYQSI GLDPSTGMHL PEAPNKHGFY
QCTWEDVDSL LDPENRLHLT TEEQLKALLE KLDMVTSMRT SGGRTKRIRL LRREINALRQ
KMSQQQNVHA SPPKRSRGKP ALAKVPSKEN GDISSSGKSA LLSIDSETEL SPLDLVWAKC
RGYPSYPAMI VDPDMPQEGL LHNGIPIPVP PGEVLKLGEW RHTDKGHKLF LVLFFDTKRT
WQWLPRNKLL PLGMDDTVDK LRLMEGKKPS VRKSVHTAYD RAMVHLNHVR RNLNFTPSNF
I
//
