ID A0A3B3Z4H6_9TELE Unreviewed; 633 AA.
AC A0A3B3Z4H6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Interferon-induced GTP-binding protein Mx {ECO:0000256|ARBA:ARBA00015210};
DE AltName: Full=Interferon-inducible Mx protein {ECO:0000256|ARBA:ARBA00031810};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000034328.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000034328.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. Dynamin/Fzo/YdjA family. {ECO:0000256|RuleBase:RU003932}.
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DR AlphaFoldDB; A0A3B3Z4H6; -.
DR STRING; 48701.ENSPMEP00000034328; -.
DR Ensembl; ENSPMET00000029952.1; ENSPMEP00000034328.1; ENSPMEG00000023441.1.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd08771; DLP_1; 1.
DR Gene3D; 1.20.120.1240; Dynamin, middle domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR019762; Dynamin_GTPase_CS.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR003130; GED.
DR InterPro; IPR020850; GED_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11566; DYNAMIN; 1.
DR PANTHER; PTHR11566:SF225; INTERFERON-INDUCED GTP-BINDING PROTEIN MXA-RELATED; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF02212; GED; 1.
DR PRINTS; PR00195; DYNAMIN.
DR SMART; SM00053; DYNc; 1.
DR SMART; SM00302; GED; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00410; G_DYNAMIN_1; 1.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS51388; GED; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003932};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003932}.
FT DOMAIN 30..303
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT DOMAIN 547..633
FT /note="GED"
FT /evidence="ECO:0000259|PROSITE:PS51388"
SQ SEQUENCE 633 AA; 72328 MW; B0D35C24D24695CB CRC64;
MNSLNQQYEE KVRPCIDLID SLRSLGVEKD LALPAIAVIG DQSSGKSSVL EALSGVALPR
GSGIVTRCPL ELKMKRRKEG QDWYGKISYQ EFEEELNDPA IVEKKIREAQ DEMAGVGVGI
CDDLITLEIA SPDVPDLTLI DLPGIARVAV KGQPENIGDQ IKRLIDKFIR KQETISLVVV
PSNVDIATTE ALKMAQQVDP DGERTLGILT KPDLVDKGTE EMVVEIVNNE VIQLKKGYMI
VKCRGQKEIT EKVSLTEAIE REKEFFKNHP YFHTLYNKEL ATIPILAEKL TIELVHHIEK
SLPRLEEQID EKLKQTQMEL DRYGNGPPSD AAERLVFLID KVTAFTQDAI SLTTGEELKC
GERLNVFTVL RREFGKWKAH LDNSGENFNR KIEREVEEYE ERYRGRELPG FINYKTFEVM
VKEQIRQLEE PAIRKLKDVG DAIKKTFIQL AHNSFTGFPN LLKTTKAKIE AIKQLKESSA
ELMLRTQFQM ELLVYSQDKT YSTSLTESKS EEEKEEAAIN NKGFKLPTTS LLSSRSTVFC
MDNHATLQEL MVHLKSYYKI AGMRLADQIP LVIRYEMLQQ SAIQLQREML QMLQDKENVD
FLLKEDYDIG NKRDALQSRT KRLMEARRYL AEF
//
