ID   A0A3B3Z5A5_9TELE        Unreviewed;       683 AA.
AC   A0A3B3Z5A5;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=SAM domain-containing protein {ECO:0000259|PROSITE:PS50105};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000034812.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000034812.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the SCM family. {ECO:0000256|ARBA:ARBA00008469}.
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DR   RefSeq; XP_014837045.1; XM_014981559.1.
DR   RefSeq; XP_014837046.1; XM_014981560.1.
DR   RefSeq; XP_014837047.1; XM_014981561.1.
DR   RefSeq; XP_014837048.1; XM_014981562.1.
DR   AlphaFoldDB; A0A3B3Z5A5; -.
DR   STRING; 48701.ENSPMEP00000034812; -.
DR   Ensembl; ENSPMET00000030686.1; ENSPMEP00000034812.1; ENSPMEG00000024197.1.
DR   GeneID; 106914642; -.
DR   KEGG; pmei:106914642; -.
DR   CTD; 10389; -.
DR   OrthoDB; 2908161at2759; -.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd20092; MBT_dScm-like_rpt2; 1.
DR   CDD; cd09578; SAM_Scm; 1.
DR   Gene3D; 2.30.30.140; -; 2.
DR   Gene3D; 3.90.1150.190; SLED domain; 1.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR   InterPro; IPR004092; Mbt.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR047531; SAM_Scm-like.
DR   InterPro; IPR033763; SCML2_RBR.
DR   InterPro; IPR021987; SLED.
DR   InterPro; IPR038348; SLED_sf.
DR   PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR   PANTHER; PTHR12247:SF84; SEX COMB ON MIDLEG-LIKE PROTEIN 2; 1.
DR   Pfam; PF02820; MBT; 2.
DR   Pfam; PF17208; RBR; 1.
DR   Pfam; PF00536; SAM_1; 1.
DR   Pfam; PF12140; SLED; 1.
DR   SMART; SM00561; MBT; 2.
DR   SMART; SM00454; SAM; 1.
DR   SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR   SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR   PROSITE; PS51079; MBT; 2.
DR   PROSITE; PS50105; SAM_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT   REPEAT          33..131
FT                   /note="MBT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT   REPEAT          139..240
FT                   /note="MBT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT   DOMAIN          615..681
FT                   /note="SAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50105"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          260..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          320..378
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          516..613
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..21
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        260..280
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        516..535
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   683 AA;  75094 MW;  56F152B67037392C CRC64;
     MGRTPQRDPK EEKKERRSSI TAGSALDKSN EPFSWEDYLR ETSSVAASPS CFKQSRIPPS
     NDFKAGMKLE ARDPRNSNSV CIATVMGMMG TRLRLRLDGS DNTNDFWRLV DSSDIQPIGT
     CERTGDMLQP PLGFRMNASS WPMFLLRTLS GAEIAPASAF KKEPSSPDKN YFQPGMKLEA
     VDRKNPYLIC PATVGEVRGL EIFVMFDGWR GAFDYWCPFD SRDIFPVGWC ALTKHSLQPP
     GNFFTLPGAL LAPVSSTSAT RRSSFNSSSS STSMQTSYRL PNPLPPLPVR KGVRGRRPKS
     QTIALLKAAA EAAAAAAAAV NGAPQSPVTE PSLAPRPHKK RGPKPKGKKK PLMGQSPGSS
     PVTTPPPEVK LNPSHVSVDS NLSNGSNVIC TVCVYVNKHG NYGPHLDRKL VQQLPDHFGP
     APVNAVLQQA VQACVDCTYQ PSVLLSFLQS QSHSGGEVIR VCSEHGIRYV KLPSASSASS
     VLRFLENMCQ HLESDSLFSS QPFNPYSNNT RFYNRTKSEP LSITENGVSN DNPTKDPTPS
     PRPLHNTLDY RAAKRERPCY PGHTQTPPPL RRVSSNPPEL GPVNTHRRVE AASSTTGPDH
     MKQDRETSGN NASSWSVDEV IRFVQEADPQ TLGPHVDLFR KHEIDGKALM LLRSDVIMKY
     MGLKLGPALK LCHHIEKLRQ TKH
//