ID   A0A3B3Z9X6_9GOBI        Unreviewed;       389 AA.
AC   A0A3B3Z9X6;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=IRS-type PTB domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Periophthalmus magnuspinnatus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX   NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000001211.1, ECO:0000313|Proteomes:UP000261520};
RN   [1] {ECO:0000313|Ensembl:ENSPMGP00000001211.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3Z9X6; -.
DR   STRING; 409849.ENSPMGP00000001211; -.
DR   Ensembl; ENSPMGT00000001280.1; ENSPMGP00000001211.1; ENSPMGG00000001094.1.
DR   Proteomes; UP000261520; Unplaced.
DR   GO; GO:0005158; F:insulin receptor binding; IEA:InterPro.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:InterPro.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR039011; IRS.
DR   InterPro; IPR002404; IRS_PTB.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR10614; INSULIN RECEPTOR SUBSTRATE; 1.
DR   PANTHER; PTHR10614:SF8; INSULIN RECEPTOR SUBSTRATE 3; 1.
DR   Pfam; PF02174; IRS; 1.
DR   PRINTS; PR00628; INSULINRSI.
DR   SMART; SM01244; IRS; 1.
DR   SMART; SM00310; PTBI; 1.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   PROSITE; PS51064; IRS_PTB; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
FT   DOMAIN          18..111
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          129..235
FT                   /note="IRS-type PTB"
FT                   /evidence="ECO:0000259|PROSITE:PS51064"
FT   REGION          261..312
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        285..312
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   389 AA;  44028 MW;  06BF3351046EE087 CRC64;
     MHNAQRLLEP FPLLCLPVKP IPGYLGKQEQ KHRRYFVLRA GSHSGPSRLE WYKTQERFTA
     VETSAGETGL FGSHKKDYKV ALYAKDQTLV FVGKDDEEQQ EWYTAIKESA AQSHVCECTK
     FWILGFTCVF QVWPVTVKPR GLGRSKALTG EILLCLTASS LVLVRVGHDH ELPSVTLPLL
     AVRRFGHLDG SFFLELGRSA PHGPGEIWME ARNLSLAQQI HEIVREAVRA LRVIPDFNWS
     SSPSKSSGSL YHSLFALKRS RPKQREKQGH CRPSGPQVLC ESLHSHSHSD PDMEETLRTD
     SVRTEPSSEP EAECYMEMKT EHSPPREGPG YVLMTPQLSQ SLHQDDYVSM TSPQKEALTK
     QASLSFLQTS FRYDPVPVFM FTMRSRTSD
//