ID A0A3B3ZAT3_9GOBI Unreviewed; 3301 AA.
AC A0A3B3ZAT3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
OS Periophthalmus magnuspinnatus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000001687.1, ECO:0000313|Proteomes:UP000261520};
RN [1] {ECO:0000313|Ensembl:ENSPMGP00000001687.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 409849.ENSPMGP00000001687; -.
DR Ensembl; ENSPMGT00000001797.1; ENSPMGP00000001687.1; ENSPMGG00000001459.1.
DR Proteomes; UP000261520; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 27.
DR Gene3D; 2.60.40.60; Cadherins; 27.
DR InterPro; IPR039808; Cadherin.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR PANTHER; PTHR24027; CADHERIN-23; 1.
DR PANTHER; PTHR24027:SF422; NEURAL-CADHERIN 2-RELATED; 1.
DR Pfam; PF00028; Cadherin; 24.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 27.
DR SUPFAM; SSF49313; Cadherin-like; 27.
DR PROSITE; PS00232; CADHERIN_1; 12.
DR PROSITE; PS50268; CADHERIN_2; 27.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..3301
FT /note="Cadherin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017404221"
FT TRANSMEM 3042..3065
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..108
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 109..212
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 213..324
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 325..434
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 435..535
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 536..645
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 646..752
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 753..864
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 865..966
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 967..1073
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1074..1179
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1181..1284
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1285..1388
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1390..1497
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1499..1604
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1605..1714
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1729..1821
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1822..1929
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1930..2039
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2040..2144
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2145..2263
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2267..2372
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2373..2479
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2480..2581
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2584..2693
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2700..2821
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 2822..2942
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 2779..2799
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3262..3301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3274..3291
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3301 AA; 363117 MW; 04112ECAEC404BD7 CRC64;
LWCMHSLRMW VFKLLLVLGR SWLSPGLSVT KLEAVDPESD PLTYGIMGEE AMKFFTVETD
GRVWLRQPLD RETKSEMQVE FTVTDSHELV TGTVNIQIGD VNDNAPTFHG QPYTVQIPED
TVRGTAVFTV NATDPDQGTG GSVLFSFQPP SDVFAIDGAR GTVTVIKPLD YERTASYQLT
INATDQDKKK PLSRLANLAI SITDVQDMDP IFTNLPYSTN IRENVPQGYV VRKITAIDQD
LGRPRPIAYR IISGNTNHVF ALDFLSGDLT VNGQLDRENP LYSAGFTLTV EATERKDDRT
LSDASVRTNF TVLLIDENDN APMFNSSEYK VTITELAQVG FALPLFIQAE DKDEGVNSMF
QVFLTGNNSE YFTISPTAVQ GRADIRMRVA KPLDYETIRS FSFSLFANES LSDHVGFARV
FIDLINENDN RPIFSSPLYN ISLPENTPVG TSLVRILATD GDDGIFGVVR YYFSDDPDQF
SLDPESGWVT LQAALDYELM RRFTLTVLAR DGGGEVTTGR IRINVLDIND NTPLFQKEMY
VGSLRENEEA IIPVARVRAT DDDSPPNNFL TYTMTSISAF PSYFSIIMVE GFAVISVMKP
LDYERIPGGV IHITVMAKDG GNPPLNSSVL VVVEVIDEND NPPTFSEPSY IVRIPENINA
GATVLLVNAT DLDASREFGQ ASLIYSLEGS TQFRLNSRSG EITTTALLDR ELKAEYILIV
RAVDGGVGPQ QKTGIATVNI TVLDINDNAP KWPDEPYYAN VVEKSPINTD VISVLAYDPD
NGDNGTVVYS ISPENPFYTI NRNNGKIRTS GVTLDRESTN PRDAALMRTI IISAVDRGTP
PLQATSSTTV FVNLQDLNDN DPTFLNLPFV AEVPEGLPIG SSVQVEDPDE DRNGLITMAL
QMGMPRLDFF LNTSTGVLSS TAVLDREQIG QYQLRIIAYD AGKFPRTSTS TLTVSVLDVN
DETPTFNPRL YNVSLKESVP RDHVVARLLC TDNDTGLNAE LSYFITGGNQ DGKFSVGFRD
GIVRTVVGLD RETQASYTLI IEAIDNGPAG SRRTGTATVF VEVQDVNDNR PIFLQNSYET
SVLETVPEGT SILQVQATDA DQGENGRVLY RILNGNSNGW FSINNQTGLI TRGRRALDRE
TSSSHVLEVE AFNSDEGSMR SSVRVIVYVD DANDEVPVFT QQQYNRLSLR ETAGIGTSVI
VVRATDPDTG DGGAVAYDIV SGADRKFQVD SSTGLVTTVE YLDYETKTTY LMNISATDQA
PPFHKGYCTV YVTLLNEADE AVAFFSAGYE ASLRENIATG TEVVQVQAQS ADNLNQLTYR
FDPDTSPVAL ALFRIDSVTG RITVTGLLDR EKGDTYTLTV VADDGGPKKD STVVSITILD
ENDNSPEFDI TSDTSVDIFE DTPMGKKVAV VLARDKDAGL NGLVNFTLVA GNMQDVFKIK
TVNHTYGEVF VNAFLDRESV DRYLLKVRAT DNGAPPRYTD HSLTINILDV NDNAPVIQSQ
RGYNVSISEN VGGGTSVLRV IATDRDIGPN AMLFYYITSG NQDLTFRMDR VTGEMVTRPA
PPDRERQEEY LLTVTVEDDG NPPLSTSTTI YVRIIDENDN APEFPEEEYE TVLSEGPETV
GATIATVTAI DPDEGLNGTL RYAITQGNLI QTFNINSISG RITAVKPLDY EISNGHYTLV
VTATDQCPIP RLRLTSSTTV LVNVLDINDV TPTFPRPYEG PFEVTEGQPG PRVWTVKATD
EDSGLNGKIE YSITAGDYQN EFMVSPVEGE LRVRKDVELD RETTGFYNIT VTARDLGTPS
RNSSVVVGVL VLDINDNDPV ILNLPFNTSV SEGAPVHYSV ARVRATDADS GRNALLTYNI
TAGNVDGAFY INDTTGVVHV NRPLDRERVA EYRLTITVKD NPENPRIARR DSDTMVITIL
DENDNRPLFS RTSYRAEITE NSAPGSTVTV LNGPVLAEDK DINQNAVVKY NLTGARVDLF
TVNPDTGVIL VRAGANLDRE AFLEPRVELF IVAEDIGGLN SSVPLSVTIL DQNDNPPVFN
PSSFSVRLPE NSPTGVVVTQ LSATDADSGA NGWLSYRLES GAQDRFVVDS ISGAVLVGNS
TLDREERGSY RLVVMATDRG TPPLTGTATL TVILDDVNDS RPRFIEPVTI INVNESTPPG
VVVATLTAED PDLHPRLEYY IISVEAKDDG NNPVGGLQDS FGIDLHTGAV FVRNPLNREL
VATFEIIVSV HDNASEVIDK SGSVPNARLT INVLDVNDNA PRFRPFGVTN FTEKILEGAQ
PGTTLLSVSA VDPDKGPNGQ VIYQLLHLPR GDYVRLEDPS TGKIVANQTV DYEQIHWLNF
TIRAQDHGTP PRIAELPVYL RIVDVNDNNP IFLQPAYHEP VFENVNLGAT VVRVQATDAD
SGLFAVLEYS LVDGEGKFGI RPTTGEIYIL SPLDRETKDH YTLTAVARDN PGGSPNNRRE
NSVQVLITVL DINDYQPRFS ERIYNTSVFE NEPSWTSIIT IKATDLDEGE NGAILYTMLG
ANTDAFALDP NTGLIRSRRM LLSSEHFNLT VVATDQGRPP LWGTATLIIT VIDVNDNRPV
FVRPANGTII HISEEQPPGL PVYEVHATDA DEGVNGEVRY AFLQTGAGNR DWENFHIDAM
TGVITTTVKL DREKQALLSL IIVARDMGQP VPYETTQPLQ VALLDIDDNE PVFLKPPGGG
PPYQTLKVPE HSPPGTIVGQ VTSAVDADEG SNAIVYYFIA GKNTDGNFAL SLDGELRLTK
DLDREETPVF SIIIKASSNK SWTPPRGSRA SRPRNMDPAR DPSLLEVRIV LEDINDQTPR
FTKAEYTAGV ATNAKVGSEL IKVVAIDNDI GNNSIVHYHI VTTQYFQTQN NGSEVVGNVF
TIGLTDGIIR TYDLFGAYKP GYFQMEVLAC DIDGRCTTSN VNIYILRDDQ RLKIVFNEIP
DIVRENQEEF LNLLSNITGA IVNLDDIQFH VDKKNRVNYG QTDMLIHVVN NETNTILDVE
RVIQMIDENK EQLRNLFRKY SVVDVQPAVS DKLPDDLSTL QLVIIILAVL LCLAGILFIT
MNWHYRRVHE RKLKAVVAGS SGNPGLMDIL DMPNTNKYSF EGANPVWMDP FCRNMELAVQ
ADHEDDLPEN LSDIADLWNS PARTHGTFGR EPQAKPEDDR YLRAAIQEYD NIAKLGHLMR
DGPIKLIQSD LDDDDDERLG MGGGGRGTLR FKHKLPMELK GPEGVHVVHG STGTLLSSDI
NSLPEDDQRA LARSLEALNS DGGLYSERNA RTESAKSTPM HRHKDGDTHT LSDSPLEITE
L
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