ID   A0A3B3ZFB3_9GOBI        Unreviewed;       541 AA.
AC   A0A3B3ZFB3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=Zinc transporter ZIP12 {ECO:0000256|ARBA:ARBA00040591};
DE   AltName: Full=Solute carrier family 39 member 12 {ECO:0000256|ARBA:ARBA00042541};
DE   AltName: Full=Zrt- and Irt-like protein 12 {ECO:0000256|ARBA:ARBA00042971};
OS   Periophthalmus magnuspinnatus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX   NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000003315.1, ECO:0000313|Proteomes:UP000261520};
RN   [1] {ECO:0000313|Ensembl:ENSPMGP00000003315.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC       {ECO:0000256|ARBA:ARBA00006939}.
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DR   AlphaFoldDB; A0A3B3ZFB3; -.
DR   STRING; 409849.ENSPMGP00000003315; -.
DR   Ensembl; ENSPMGT00000003516.1; ENSPMGP00000003315.1; ENSPMGG00000002872.1.
DR   Proteomes; UP000261520; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR003689; ZIP.
DR   InterPro; IPR041137; ZIP4_N.
DR   PANTHER; PTHR12191; SOLUTE CARRIER FAMILY 39; 1.
DR   PANTHER; PTHR12191:SF4; ZINC TRANSPORTER ZIP12; 1.
DR   Pfam; PF02535; Zip; 2.
DR   Pfam; PF18292; ZIP4_domain; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        279..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        309..337
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        357..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        453..473
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        479..500
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        512..535
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          12..146
FT                   /note="Zinc transporter ZIP4 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18292"
SQ   SEQUENCE   541 AA;  60148 MW;  5794EBD37D8E523F CRC64;
     LCFFKVNHVL NKRSPLLTEE DYQKISTVLL YYIINLQDLC MPNMASSLTS SSLSSSSENY
     QFYLLALANL HPAEDNLFLS FNETGSVLQL INRHYHPVHQ ESDMQCVDAA HLLRKIDVGE
     DPGADMSTVP KLSAAIISHM LLGHCFQQRN LPSPTFFTDY IFESLNSQTV AEPRLDQLWE
     ACTCLRIKQL PVIGPRWDFG ETLHILVYAL TYNNIVALSQ VCFSANQLVD IFALDPYLPI
     SKDHFRQICP AIIQQLLGNA CESTESNTRG PQPTALEKYG YSTIAVLLIT LGSMLGTCLI
     FFHSCQETYT LILQLFVGLA VGTLSGDALL HLIPQILGLH EHDHIKKEHF AEGKDHLWKL
     LGMIAGIYAF FLLEKIFTPF VFSGQGVPLL AVMVIVGDSL HNFADGLVIG AAFSSSAETG
     MATTVAILCH EIPHEMGDFA VLLNSGLPVK TAVLMNFLSA LTAFMGLYIG LFVSAEAQVQ
     QWIFSVTAGI FLYLSLVEML PEMSRVKTTR PCLMFFLQNL GLLMGWACLL LLALFEHELR
     L
//