ID   A0A3B3ZFI4_9GOBI        Unreviewed;       801 AA.
AC   A0A3B3ZFI4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPMGP00000003166.1};
OS   Periophthalmus magnuspinnatus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX   NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000003166.1, ECO:0000313|Proteomes:UP000261520};
RN   [1] {ECO:0000313|Ensembl:ENSPMGP00000003166.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the retinoblastoma protein (RB) family.
CC       {ECO:0000256|ARBA:ARBA00009475}.
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DR   AlphaFoldDB; A0A3B3ZFI4; -.
DR   STRING; 409849.ENSPMGP00000003166; -.
DR   Ensembl; ENSPMGT00000003359.1; ENSPMGP00000003166.1; ENSPMGG00000002748.1.
DR   Proteomes; UP000261520; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   GO; GO:0051172; P:negative regulation of nitrogen compound metabolic process; IEA:UniProt.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   CDD; cd20599; CYCLIN_RB; 1.
DR   Gene3D; 1.10.472.140; -; 1.
DR   Gene3D; 6.10.250.530; -; 1.
DR   Gene3D; 1.10.472.10; Cyclin-like; 2.
DR   InterPro; IPR013763; Cyclin-like_dom.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR002720; RB_A.
DR   InterPro; IPR002719; RB_B.
DR   InterPro; IPR015030; RB_C.
DR   InterPro; IPR028309; RB_fam.
DR   InterPro; IPR024599; RB_N.
DR   PANTHER; PTHR13742:SF17; RETINOBLASTOMA-ASSOCIATED PROTEIN; 1.
DR   PANTHER; PTHR13742; RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED; 1.
DR   Pfam; PF11934; DUF3452; 1.
DR   Pfam; PF01858; RB_A; 1.
DR   Pfam; PF01857; RB_B; 1.
DR   Pfam; PF08934; Rb_C; 1.
DR   SMART; SM00385; CYCLIN; 1.
DR   SMART; SM01367; DUF3452; 1.
DR   SMART; SM01368; RB_A; 1.
DR   SMART; SM01369; Rb_C; 1.
DR   SUPFAM; SSF47954; Cyclin-like; 2.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618};
KW   Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW   Cyclin {ECO:0000256|ARBA:ARBA00023127};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          56..172
FT                   /note="Retinoblastoma-associated protein N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01367"
FT   DOMAIN          312..504
FT                   /note="Retinoblastoma-associated protein A-box"
FT                   /evidence="ECO:0000259|SMART:SM01368"
FT   DOMAIN          550..637
FT                   /note="Cyclin-like"
FT                   /evidence="ECO:0000259|SMART:SM00385"
FT   DOMAIN          658..801
FT                   /note="Retinoblastoma-associated protein C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01369"
FT   REGION          766..801
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        774..790
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   801 AA;  91892 MW;  4B67CBF219346584 CRC64;
     HRDKDTEFVI FCKNLHVSDL VCEQTWKLWK TVQETVNEVL EGRAKLWGAC LFVTITDMDT
     ACFTLTQLLK AVNMVKGFLG LVRKLDVNLD TISTKVNAAV MRLEKKYDVT LALYQRFETC
     KKIFVLGSNE NQELSRNCWT LFLLAKKALQ MEDDLVISFQ LLLCVMEYFI KRCPADLVQP
     LYSVITVQSP PTRTSRRSQN KAKARPPEPE LDVRLLETLS KENECNAEEV KNVYQTSFTA
     FLESLHLLKS IDLPQILKEQ YEEHYLKERD FDARLFLDGD ETIFAPKIET QVEKTPQKNL
     QEDDAVRIIP QTPIAAMTSI QQLRGDLVSN GDKPSTNLNT YFKNCTVDPT QNVLKRLETL
     GQTFSQRFSQ AVGPRLGVRL YYKVMEAMLK SEEKRLSVQN FKLLNDSKFH TSLLACALEV
     VMATYGSSFK SGGNGSESSE SNLCFPWILD VFELAAFDFY KVIESFIKAE PTLSKDIVKH
     LETCENLIME KIAWVMGSPL FDLLKLEQEA DAAETPVETP ANLNQPLQHN HTAADNSLSL
     FYKKYRLAYT RLKMLCSYLL SYHPELEPII WTLFQHTLQH EYELMRNRHL DQLMMSAMYA
     IAKVKSVDLR FKTIVTAYKN MPNTKQETFK QVLISEGNYD SIIVFYNQVF MQRLKTNILQ
     YASPRPPTLS PIPQIPRSPY HFPNSPLRVP GSNNVYISPL KSTRMSPGIM TPRSRMLVSI
     GESFGQLSNR FQKINQMVNS SDRSYKRTLD LGPSLKPLKR LRFDVDGQDE ADGKSSGDST
     LIQKLAEMST RSRMQEQKMK E
//