ID A0A3B3ZGT1_9GOBI Unreviewed; 1134 AA.
AC A0A3B3ZGT1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPMGP00000003606.1};
OS Periophthalmus magnuspinnatus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000003606.1, ECO:0000313|Proteomes:UP000261520};
RN [1] {ECO:0000313|Ensembl:ENSPMGP00000003606.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the formin homology family. Diaphanous
CC subfamily. {ECO:0000256|ARBA:ARBA00008214}.
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DR AlphaFoldDB; A0A3B3ZGT1; -.
DR STRING; 409849.ENSPMGP00000003606; -.
DR Ensembl; ENSPMGT00000003829.1; ENSPMGP00000003606.1; ENSPMGG00000003102.1.
DR Proteomes; UP000261520; Unplaced.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR Gene3D; 1.20.58.630; -; 1.
DR Gene3D; 6.10.30.30; -; 1.
DR Gene3D; 1.10.20.40; Formin, diaphanous GTPase-binding domain; 1.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.10.238.150; Formin, FH3 diaphanous domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014767; DAD_dom.
DR InterPro; IPR044933; DIA_GBD_sf.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR PANTHER; PTHR45691; PROTEIN DIAPHANOUS; 1.
DR PANTHER; PTHR45691:SF4; PROTEIN DIAPHANOUS HOMOLOG 1; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF06371; Drf_GBD; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51231; DAD; 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils}.
FT DOMAIN 57..420
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 629..1025
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT DOMAIN 1047..1075
FT /note="DAD"
FT /evidence="ECO:0000259|PROSITE:PS51231"
FT REGION 21..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 587..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 466..518
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1002..1043
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 21..37
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 587..628
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1134 AA; 129123 MW; B529528CEF1C1F94 CRC64;
QQGLGLGLGP FRKEIESSLE RFTSMRMKKD KEKPGQMPSQ RHSSAASYEF SSQSPMMQDH
SDEYVLELFE QMLVDMNLNE EKQQPLREKD IVIKREMVSQ YLHTSKAGQN QKESSRSAVM
YIHELQEDYR DPQLLLSCLE SLRVSLNNNP VSWVQTFGDQ GLTLLLTRLR GLQEDKHEMA
IKCQHEIIRC LKAFMNNKYG LKSMLESGEG IPLLVRAMNP TVPHMMVDAV KLLSAISILE
HPENLHERVL EAITEEAEKR NIERFQPLLS GMNIHNIALK VGGCMQLINA LISRGEELDF
RIHIRSELLR LGLRHQLMEI RTIENEELRV QLAVFDEQAE DDSEDLRARL DDIRIEMEYL
FNGVFEILVN TVKDSKAEGN FLSVMQHLLL IRNDYLARPQ YYKLIDECIG QIVLHKNGAD
PDFKCRHLNL NIESLIDNMV DQTKVETSEA KATELEKKLN TELTARHELQ VELKKLEGDY
EQKLQDLSQE KEQLASVKQE REKENQGLHK QLSSLQLQVP AHHLVLSFSL VNASHSTVGC
PHHHLCLPQP LRVLELDLHH LLHAMQACLC PHLLRLLRLL HLPGMGPPPP PPPPGGPGVP
PPPPGPGMPP PPFGGWTAAP PPLPYGLQPK KEYKPEVQLK RANWSKIGPE DLSESSFWTK
AKEDQFGNNE LFAKLTLTFS SQTKTKNVPD GGDDKKNMQK KKAKELKVLD GKSAQNLSIF
LGSFRLPYEE IKNAILEVNE KILTESMVQN LIKQLPSPEQ LSVLAEMKDE YDDLAESEQF
GVVMSSVKKL TPRLQAILFK LQFEEQLNNI KPDVVSVTAA CEELTKSQSF SQLLQIILLM
GNFMNAGSRN GKAFGFSISY LCKLRDTKST DLKMTLLHFL AEVCQEQYPE VMSFPDELIH
VEKASRVSAE TIQKNLELMG RQIKNLQKDL ETFPPPQNEK DQFAENFVGT AQEQYEKLDL
MHKNMDKQYT DLGNYFVFDP RKISVEEFFG DLKTFINMFQ QAVKENQKRK ESEEKIKRAK
LAREKAEKEK EEKLKRSQLL DINAEGDETG IMDGLLEALQ SGAAFRRKRG PRQAVLRCTA
AVSQCGLRMA ILVSTKLSTL SAFIPTIMSY LFYTVASFNT NKHGCLCVQP QLQQ
//
