ID   A0A3B3ZGX6_9GOBI        Unreviewed;       995 AA.
AC   A0A3B3ZGX6;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=DAB2 interacting protein b {ECO:0008006|Google:ProtNLM};
OS   Periophthalmus magnuspinnatus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX   NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000003651.1, ECO:0000313|Proteomes:UP000261520};
RN   [1] {ECO:0000313|Ensembl:ENSPMGP00000003651.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3ZGX6; -.
DR   Ensembl; ENSPMGT00000003884.1; ENSPMGP00000003651.1; ENSPMGG00000003139.1.
DR   Proteomes; UP000261520; Unplaced.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   CDD; cd04013; C2_SynGAP_like; 1.
DR   CDD; cd05136; RasGAP_DAB2IP; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR021887; DAB2P_C.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR039360; Ras_GTPase.
DR   InterPro; IPR023152; RasGAP_CS.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   PANTHER; PTHR10194:SF26; DISABLED HOMOLOG 2-INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR   Pfam; PF00168; C2; 1.
DR   Pfam; PF12004; DAB2P_C; 2.
DR   Pfam; PF00616; RasGAP; 1.
DR   SMART; SM00239; C2; 1.
DR   SMART; SM00323; RasGAP; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468}.
FT   DOMAIN          1..91
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          82..200
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          257..449
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
FT   REGION          645..666
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          679..811
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          966..995
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          838..904
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        688..724
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        727..741
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        757..796
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   995 AA;  112198 MW;  418AA223994E007D CRC64;
     TLSQPKLCRH SNNTPRCVMR AVGGDSLLST GSVSSLDLRM DQSVIIKPVH SSLLGQDYCF
     EVTTSSGTKC FSCRSAAERD KWMENLRRAV LPNKDNIRRT ENLLTLWVLE GRDLGPKKRY
     FVEVCLDDCL YARTSCKSRT DNVFWGERFD FSALPSIGAI TLHLYKETNP KRRKDKSSYV
     GLVNISVSAL IGRQVQERWY QLSTPSSRKS GPALRVRVQF QSVVVLPMEQ YKEFAEWISA
     NYLRLCGTLE SNLSLRSKDE ISAALVHILH STGKAKDFLT DLMMAEVDRC RDNDQLIFRE
     NTLATKSIEE YLKLIGHKYL QDALGEFVKA LYESDENCEV DPSRCSTSDL QEHQANLRMC
     CELAFCKILD SYRVFPRELK EVFCSWKEEC VSRGRGDISE RLITASLFLR FLCPAVMSPS
     LFQLCSEYPD DRTARTLTLI AKVIQNLANF SKFGSKEDYM VFMNDFVERQ WSAMQRFVQE
     ISSLESLNQG QGFEGYIDLG RELSTLHSLL KSVSDSLFSQ SLLVKLPPLP RIIRELSLAL
     ANPGGVVSAA GEEDLNRFLV GLFRLVDFTR LPSPTPENKE LFFVTKGSSL RMSPSSSYSD
     PNEANDANEA NIDDAALDSA TGDELDDEGA WRRAGLLPLS FQNPVYHMTT PSPRQPSSEA
     TPLELSQDTA TKPAFLTQMS DPAHFPTDPA PFQKPLPDPT PFQKPHQDPS PFQKPLPDPT
     PFQKPLPERL SSGTRQTGPQ RRIDQPPPAA PPRGRTPPTV LTSSAHYPRP ASGSMMSSSP
     DWPSSRLRQT SSSSKGDSPE KQRKAPSPCA LDRTAAWLLN MNSSYGETEE ERHEDATIEK
     YQQEILALQE KLRVAALREE ECESRLLVQD QQNQRMLQEY QVRLEDTESR LRRLQDDKDL
     QMNSIITRLM AVEEELKKDH SDMQAVVDSK QKIIEAQEKR ILSLDAANTR LMAALTQLKE
     RYAVTSRNGL SPSNTSSLQI TENGEFRTNP GLNQD
//