ID A0A3B3ZH52_9GOBI Unreviewed; 623 AA.
AC A0A3B3ZH52;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPMGP00000003872.1};
OS Periophthalmus magnuspinnatus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000003872.1, ECO:0000313|Proteomes:UP000261520};
RN [1] {ECO:0000313|Ensembl:ENSPMGP00000003872.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the DSH family. {ECO:0000256|ARBA:ARBA00008735}.
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DR AlphaFoldDB; A0A3B3ZH52; -.
DR Ensembl; ENSPMGT00000004118.1; ENSPMGP00000003872.1; ENSPMGG00000003307.1.
DR Proteomes; UP000261520; Unplaced.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd04438; DEP_dishevelled; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.240.130; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR024580; Dishevelled_C-dom.
DR InterPro; IPR008339; Dishevelled_fam.
DR InterPro; IPR003351; Dishevelled_protein_dom.
DR InterPro; IPR001158; DIX.
DR InterPro; IPR038207; DIX_dom_sf.
DR InterPro; IPR015506; Dsh/Dvl-rel.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10878; SEGMENT POLARITY PROTEIN DISHEVELLED; 1.
DR PANTHER; PTHR10878:SF6; SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-3; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF02377; Dishevelled; 1.
DR Pfam; PF00778; DIX; 1.
DR Pfam; PF12316; Dsh_C; 1.
DR Pfam; PF00595; PDZ; 1.
DR PRINTS; PR01760; DISHEVELLED.
DR SMART; SM00021; DAX; 1.
DR SMART; SM00049; DEP; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50841; DIX; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687, ECO:0000256|PROSITE-
KW ProRule:PRU00069}.
FT DOMAIN 1..82
FT /note="DIX"
FT /evidence="ECO:0000259|PROSITE:PS50841"
FT DOMAIN 220..292
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 393..457
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT REGION 88..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 186..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 470..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 510..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..154
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..542
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 564..584
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 623 AA; 67229 MW; 195952AEB244742C CRC64;
MGETKIIYHL DDQETPYLVK VPVPADKVTL ADFKNVLKKP NYKFYFKSMD DDFGVVKEEI
SDDNAKLPCV NGRVVSWLVS GDGALTDAGS VADSSEGAPP LERTGGIGDS RPPSYHGKAV
SGRDTLDNDA ETGSAVSQRR ERERPRRKHA NEHGGRQNGY SSRAMARGGP DYDSCSSFMS
SELESTSCFD SEDDDATSRS VSSSSFSSIT DSTMSLNIIT VTLNMEKYNF LGISIVGQSN
ERGDGGIYIG SIMKGGAVAA DGRIEPGDML LQVNDINFEN MSNDDAVRVL RDIVHKPGPI
TLTVAKCWDP NPRSCFALPR SEPIRPIDPA AWVSHTAAMT GVYPPYGMSP SMSTVTSTSS
SISSSIPETE RFDDFHLSIH SDMGTVAKAM ACPESGLEVR DRMWLKITIA NAFIGSDVVD
WLFHHVEGFS DRREARKYAS NLLKITFSEQ CYYIFGDLCG NMAHLSLHDH DGSSGASDQD
TVPPLPHPGA APWPMPVPYQ FPIPHPYELQ QPFPAGPGCG SVGSQHSGSS GSNCSKNEGR
KSGGSGSETE IRSRAPSERS VAPPSERSVR SSLSHRSPQH LSISAPGAPQ GRELSSVPPE
LTASRQSLRM AVGNAGEFFV DVM
//
