ID   A0A3B3ZLP8_9GOBI        Unreviewed;       363 AA.
AC   A0A3B3ZLP8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=Hydroxylysine kinase {ECO:0000256|ARBA:ARBA00040505};
DE            EC=2.7.1.81 {ECO:0000256|ARBA:ARBA00038873};
OS   Periophthalmus magnuspinnatus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX   NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000005558.1, ECO:0000313|Proteomes:UP000261520};
RN   [1] {ECO:0000313|Ensembl:ENSPMGP00000005558.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Catalyzes the GTP-dependent phosphorylation of 5-hydroxy-L-
CC       lysine. {ECO:0000256|ARBA:ARBA00037368}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(5R)-5-hydroxy-L-lysine + GTP = (5R)-5-phosphooxy-L-lysine +
CC         GDP + H(+); Xref=Rhea:RHEA:19049, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:37565, ChEBI:CHEBI:57882, ChEBI:CHEBI:58189,
CC         ChEBI:CHEBI:58357; EC=2.7.1.81;
CC         Evidence={ECO:0000256|ARBA:ARBA00036820};
CC   -!- SIMILARITY: Belongs to the aminoglycoside phosphotransferase family.
CC       {ECO:0000256|ARBA:ARBA00006219}.
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DR   AlphaFoldDB; A0A3B3ZLP8; -.
DR   STRING; 409849.ENSPMGP00000005558; -.
DR   Ensembl; ENSPMGT00000005900.1; ENSPMGP00000005558.1; ENSPMGG00000004657.1.
DR   Proteomes; UP000261520; Unplaced.
DR   Gene3D; 3.90.1200.10; -; 1.
DR   InterPro; IPR002575; Aminoglycoside_PTrfase.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   PANTHER; PTHR21064:SF1; HYDROXYLYSINE KINASE; 1.
DR   PANTHER; PTHR21064; UNCHARACTERIZED; 1.
DR   Pfam; PF01636; APH; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   3: Inferred from homology;
FT   DOMAIN          31..277
FT                   /note="Aminoglycoside phosphotransferase"
FT                   /evidence="ECO:0000259|Pfam:PF01636"
SQ   SEQUENCE   363 AA;  41179 MW;  94CB3DE8A05F9B0E CRC64;
     MAEKHVKPNF SPAQASDIMM RLYDLTTSQI HPLPSYDDQN FYVSSTNGND YVLKIMNSED
     SKNQSLIEVQ TFAMSFLHEN GIPAQTATPA VTGQLMSLEE LDCGFGRQNY LVRLLSYLPG
     NTISKAPVTP QLLFETGKMA AKMDKVLQKM DRPNIRELDR DGLIWSLSNL LALEKYMYVL
     DGEPLQEVVK SVIDLYKTTV VPNYLHFRKC INHGDFNDLN VLVQPNNSGC YKICGILDFG
     DMNSGFYIHE LAITIMYMMI EHPNPIEVGG AVLAGWESEL PLNEAERDCL YVLVLSRFCQ
     SLVLARYSVR MHPENEDYLM VTSRKGIHIL QDIWKLGKQH VEKVWFNSAA QQLNKVGIFC
     FGS
//