ID   A0A3B3ZTF4_9GOBI        Unreviewed;       648 AA.
AC   A0A3B3ZTF4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=T-box domain-containing protein {ECO:0000259|PROSITE:PS50252};
OS   Periophthalmus magnuspinnatus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX   NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000007591.1, ECO:0000313|Proteomes:UP000261520};
RN   [1] {ECO:0000313|Ensembl:ENSPMGP00000007591.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00201}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR   AlphaFoldDB; A0A3B3ZTF4; -.
DR   STRING; 409849.ENSPMGP00000007591; -.
DR   Ensembl; ENSPMGT00000008077.1; ENSPMGP00000007591.1; ENSPMGG00000006301.1.
DR   OrthoDB; 5323209at2759; -.
DR   Proteomes; UP000261520; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0009790; P:embryo development; IEA:UniProt.
DR   GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR   InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR   InterPro; IPR032385; T-box_assoc.
DR   InterPro; IPR046360; T-box_DNA-bd.
DR   InterPro; IPR036960; T-box_sf.
DR   InterPro; IPR001699; TF_T-box.
DR   InterPro; IPR018186; TF_T-box_CS.
DR   PANTHER; PTHR11267:SF88; T-BOX BRAIN PROTEIN 1; 1.
DR   PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR   Pfam; PF00907; T-box; 1.
DR   Pfam; PF16176; T-box_assoc; 1.
DR   PRINTS; PR00937; TBOX.
DR   SMART; SM00425; TBOX; 1.
DR   SUPFAM; SSF49417; p53-like transcription factors; 1.
DR   PROSITE; PS01283; TBOX_1; 1.
DR   PROSITE; PS01264; TBOX_2; 1.
DR   PROSITE; PS50252; TBOX_3; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00201};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00201}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          192..377
FT                   /note="T-box"
FT                   /evidence="ECO:0000259|PROSITE:PS50252"
FT   REGION          20..84
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          432..465
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          565..628
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        42..68
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        585..603
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   648 AA;  70465 MW;  CDACF2E188192937 CRC64;
     MQVEDCLSPA SGLSKKFMNV GSAFSSSDGS ELPLQDHPIL SASDNLERSS PLKKNSREMT
     NQSEADNFPD SKDAPGDVQR GKLSPALHFD GSAAERCIFS PTQPQPVSAA APSAMFPYAS
     QHAPPAFSIG SPGRYMAHHP VITNGAYNSL SQGYPAAGYP YAQQYGHAYQ GGAFYQFSSA
     QGLVPGKAQV YLCNRALWLK FHRHQTEMII TKQGRRMFPF LSFNISGLDP TAHYNIFVDV
     ILADPNHWRF QGGKWVPCGK ADTNVIGNRV YMHPDSPNTG AHWMRQEISF GKLKLTNNKG
     ASNNTGQMVV LQSLHKYQPR LHVVEVNEDG TEDTSQPGRV QTFTFTETQF IAVTAYQNTD
     ITQLKIDHNP FAKGFRDNYD TVYTGCDIDR LTPSPGDSPR SQIVPGARYA MPSSFLQDQF
     VSTYAKSRFH PGVGAGPGTE RSVPLGNSLL SPQQSEEPPV ATPPQRWFVT PANNRLDFGA
     SAYDAADFAG NAATLLSYAA AGVKALPLPT AGCSNRPLGY YADPSGWGGR TPPQYKTGSV
     FSCWPANSLS RGVNYLSEEG ADAVATERSP IGASDEPKPK DLSESSWIET PSSIKSMDSS
     DSGIFEQAKR RRISPSATPV PETVSPLKSE CDKTCTKDIG YYSFYPHS
//