ID   A0A3B3ZVS3_9GOBI        Unreviewed;       734 AA.
AC   A0A3B3ZVS3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE            EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
OS   Periophthalmus magnuspinnatus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX   NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000008833.1, ECO:0000313|Proteomes:UP000261520};
RN   [1] {ECO:0000313|Ensembl:ENSPMGP00000008833.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000256|ARBA:ARBA00001556};
CC   -!- SIMILARITY: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
CC       {ECO:0000256|ARBA:ARBA00005601}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3B3ZVS3; -.
DR   Ensembl; ENSPMGT00000009402.1; ENSPMGP00000008833.1; ENSPMGG00000006002.1.
DR   Proteomes; UP000261520; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0032574; F:5'-3' RNA helicase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProtKB-KW.
DR   CDD; cd18038; DEXXQc_Helz-like; 1.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR045055; DNA2/NAM7-like.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR049080; MOV-10-like_beta-barrel.
DR   InterPro; IPR026122; MOV-10/SDE3_DEXXQ/H-box.
DR   InterPro; IPR049079; Mov-10_helical.
DR   InterPro; IPR049077; MOV-10_Ig-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR   PANTHER; PTHR10887:SF537; HELICASE MOV-10; 1.
DR   Pfam; PF13086; AAA_11; 2.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF21634; MOV-10_beta-barrel; 1.
DR   Pfam; PF21635; Mov-10_helical; 1.
DR   Pfam; PF21633; MOV-10_Ig-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   DOMAIN          29..63
FT                   /note="Helicase MOV-10 Ig-like"
FT                   /evidence="ECO:0000259|Pfam:PF21633"
FT   DOMAIN          118..178
FT                   /note="Helicase MOV-10 helical"
FT                   /evidence="ECO:0000259|Pfam:PF21635"
FT   DOMAIN          199..263
FT                   /note="Helicase MOV-10-like beta-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF21634"
FT   DOMAIN          312..395
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          417..496
FT                   /note="DNA2/NAM7 helicase helicase"
FT                   /evidence="ECO:0000259|Pfam:PF13086"
FT   DOMAIN          503..682
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
SQ   SEQUENCE   734 AA;  82600 MW;  5025499D9C0F850E CRC64;
     HGIKITSEAL FTDGKMTLHL ESLCEVSNFN GNAIGFHPVT LAFEFKSDLK SSTSFHIVRF
     IEAHCMTTMG KELAPVVTYR PQGIHLPNKY VITDCHDSHC HFSPLSMSVM KLKHKVQLKP
     YPIPDFMNAL IIALKQQTYY SDRRKDILEA ALSWENYAEK FKLMLFLEEL QMEVDIQRYN
     IPNDNQPEVL SVGFTVSDCQ VPGVAENRPS VLRGDQLLAY PIGESNKKYR GYVHCVQLDS
     VKLGFSSELL DIFIEGMKFN IEFIINRLTL RIQHRAAEFA ERSALAPVLF PVAPPSPASQ
     QTLPDLKKLE KNPEQYRAVQ HIVAGSSKPA PYLVFGPPGT GKTVTVVEAI KQIEKCKANC
     HILACAPSNS AADLLCKKIR DHVDVSSVFR MYASSHDPML VPEEIKACSN LIGNCYEYPE
     KEKLMEYKIV VTTLITAGRL VSGDIPMGHF THVFVDESGH AVETECIVPL AGLLHPETGQ
     VVLAGDPKQL GPIIRSPLAL KLTSLSENQW SHPAILEIPN ELFYDRELQA CADEQRNFYC
     NWEYLPKMNF PVIFHGVTGL DTRESSSPSF FNIAEVEVLM DYVMKLLQTQ GKKGLSTLSP
     KDIGIIAPYR KQVQKIRKAL HIVGSVEEFQ GQERRVILVS TVRSSPDYVE IDKKFKLGFV
     KNEKRFNVAI TRAKALLIIV GNPLVLRSDP TWARFLQYCQ DQGGYRGYVQ TEEDQDIVER
     CASLYLSMEV EGIN
//