ID   A0A3B4A6W4_9GOBI        Unreviewed;       750 AA.
AC   A0A3B4A6W4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Cationic amino acid transporter C-terminal domain-containing protein {ECO:0000259|Pfam:PF13906};
OS   Periophthalmus magnuspinnatus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX   NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000012241.1, ECO:0000313|Proteomes:UP000261520};
RN   [1] {ECO:0000313|Ensembl:ENSPMGP00000012241.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3B4A6W4; -.
DR   STRING; 409849.ENSPMGP00000012241; -.
DR   Ensembl; ENSPMGT00000013058.1; ENSPMGP00000012241.1; ENSPMGG00000010101.1.
DR   Proteomes; UP000261520; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 2.
DR   InterPro; IPR002293; AA/rel_permease1.
DR   InterPro; IPR029485; CAT_C.
DR   PANTHER; PTHR43243:SF29; CATIONIC AMINO ACID TRANSPORTER-RELATED; 1.
DR   PANTHER; PTHR43243; INNER MEMBRANE TRANSPORTER YGJI-RELATED; 1.
DR   Pfam; PF13520; AA_permease_2; 1.
DR   Pfam; PF13906; AA_permease_C; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        52..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        86..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        190..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        219..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        249..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        284..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        333..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        369..402
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        408..429
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        531..550
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        556..577
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        589..612
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        618..639
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          591..641
FT                   /note="Cationic amino acid transporter C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13906"
FT   REGION          453..486
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          668..750
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        453..470
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        708..723
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   750 AA;  82053 MW;  4854ABB97C61C485 CRC64;
     MASFLSRVFS GDSAYLMYSR LVRTKPVGSM GQSGDELTEM GDSSSGVGLA KVLTMADLVS
     LGVGSCVGTG MYVVSGLVAK AMAGPGVILS FIIAAVASVL SGVCYAEFGV RVPKTTGSAY
     TYSYVTVGEF VAFFIGWNLI LEYLIGTAAG ASALSNMFDS LANHTISQYM ITHLGTLRGL
     GKGEDTYPDL LALFIVLLVT AVIALGVRNS VGFNNVLNAV NLVVWIFMII AGLFFLSARN
     WEGGNFLPYG WSGVMQGAAT CFYAFIGFDI IATTGEEAKN PNTSIPYAIT ASLVTCLTAY
     VSVSVILTLM VPYDLIDGSA PLMEMFAVHG FLWGKYIVAA GSVAGLTVSL LGSLFPMPRV
     IYAMSRDGLL FRFLCHVSAF THTPAVACVI SGIFAAILAL LVSLRDLIEM MSIGTLLAYT
     LVSVCILLLR YQPDETTDTH QFRSEDTEDI KQLEDGDFPN KDDRKLIDNE NSSYHAGGTE
     GEGDDSDFHT GHASLFKRLL GGHYYTIRMW LRMPDTSARP TPITGRTVTR CTLSFFICSF
     FMWSSVIFGV EQGSGFGAVL SGIMAALVCG TLVKLMVTIL QQPESPRRLP YMAPCVPFVP
     AAAILVNTYL MLKLRPLTWI RFTIWCLIGL LIYCCYGVWH STLELNAQEE QAQASTYQRY
     DNHLDDTFSP EFYPEEGDSE QPYQGWSAPE ERGYHYNTQR NLPGQEVPYE EGEEEEEEEE
     GEGYGYQSAP RAKYKNSRGR TNRGFFDDED
//