ID   A0A3B4A7F2_9GOBI        Unreviewed;       749 AA.
AC   A0A3B4A7F2;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Transcription factor RFX3 {ECO:0000256|ARBA:ARBA00040859};
DE   AltName: Full=Regulatory factor X 3 {ECO:0000256|ARBA:ARBA00042137};
OS   Periophthalmus magnuspinnatus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX   NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000012983.1, ECO:0000313|Proteomes:UP000261520};
RN   [1] {ECO:0000313|Ensembl:ENSPMGP00000012983.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A3B4A7F2; -.
DR   STRING; 409849.ENSPMGP00000012983; -.
DR   Ensembl; ENSPMGT00000013857.1; ENSPMGP00000012983.1; ENSPMGG00000010705.1.
DR   Proteomes; UP000261520; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR003150; DNA-bd_RFX.
DR   InterPro; IPR039779; RFX-like.
DR   InterPro; IPR007668; RFX1_trans_act.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR12619; RFX TRANSCRIPTION FACTOR FAMILY; 1.
DR   PANTHER; PTHR12619:SF20; TRANSCRIPTION FACTOR RFX3; 1.
DR   Pfam; PF04589; RFX1_trans_act; 1.
DR   Pfam; PF02257; RFX_DNA_binding; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51526; RFX_DBD; 1.
PE   4: Predicted;
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW   Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT   DOMAIN          170..244
FT                   /note="RFX-type winged-helix"
FT                   /evidence="ECO:0000259|PROSITE:PS51526"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   749 AA;  82889 MW;  F02553F20D6E5B95 CRC64;
     MQTPEAGADS TSTVPLQTTV PVQPAGSSQA QTVPQVQHVY PAQVQYVEEN SGVYTNGNRR
     SYTYSETQLY SQNSGGSYFD TQGSSPQVST VVTSHGLTNN GGGGSGGMSI GLTGAQVISS
     TSGGYLMDNA GPHTATQAAR ASPATIEMAI ETLQKSEGLS SQRSSLLNSH LQWLLDNYET
     AEGVSLPRST LYNHYLRHCQ EQKLDPVNAA SFGKLIRSIF MGLRTRRLGT GNSKYHYYGI
     RVKPDSPLNR LQEDMQYMAL RQQPVQQKQF KPVQKFDTSS GDSYSGGGQH QPGVAEQTVI
     AQSQHHQQFL DASRALPDFI ELNLGQSLTP ENISQEDVKA LQSLYREHCE QAILDVVVNL
     QFSLIEKLWQ TFWRYTPPDS AEGATVTENS ISEIEGRLPR SQLIVLCRHD SVLKWMSTCD
     HLMYQALVEI LIPDVLRPIP ALTQAIRNFA KSLEGWLTNA MNAIPQRMIQ TKIAAVSAFA
     QTLRRYTSLN HLAQAARAVL QNTSQINQML SDLNRVDFAN VQEQASWVCQ CEEGVVQHLE
     QDFKATLQQQ SSLEQWAAWL DNVVTQVLKP FEHRPSFPRA ARQFLLKWSF YSSMVIRDLT
     LRSAASFGSF HLIRLLYDEY MFYLVEHRVA QATGETPIGV MGEFDSLNSL TLTNIDKETS
     GMDSDLEDDT DTCGEPLAKR ERSEHEVIQV IQVGALEDGS HPVVGVVQPG VLHSLPQPPP
     DHSEHILTPS SATPTIRHCS ATGNTYASV
//