ID A0A3B4AD04_9GOBI Unreviewed; 285 AA.
AC A0A3B4AD04;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=poly(A)-specific ribonuclease {ECO:0000256|ARBA:ARBA00012161};
DE EC=3.1.13.4 {ECO:0000256|ARBA:ARBA00012161};
OS Periophthalmus magnuspinnatus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000014947.1, ECO:0000313|Proteomes:UP000261520};
RN [1] {ECO:0000313|Ensembl:ENSPMGP00000014947.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage of poly(A) to 5'-AMP.; EC=3.1.13.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001663};
CC -!- SIMILARITY: Belongs to the CAF1 family.
CC {ECO:0000256|ARBA:ARBA00008372}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3B4AD04; -.
DR STRING; 409849.ENSPMGP00000014947; -.
DR Ensembl; ENSPMGT00000015932.1; ENSPMGP00000014947.1; ENSPMGG00000012245.1.
DR OrthoDB; 341493at2759; -.
DR Proteomes; UP000261520; Unplaced.
DR GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:UniProtKB-EC.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProt.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR039637; CNOT7/CNOT8/Pop2.
DR InterPro; IPR006941; RNase_CAF1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10797; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT; 1.
DR PANTHER; PTHR10797:SF1; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 8; 1.
DR Pfam; PF04857; CAF1; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
SQ SEQUENCE 285 AA; 32689 MW; 727EB3AB29B61B7E CRC64;
MPAALADSSQ IICEVWASNV EDEMRKIRAI IQNYNYIAMD TEFPGVVVRP IGEFRSTVDY
QYQLLRCNVD LLKIIQLGLT FMNEDGDYPA VTTTWQFNFK FNLTEDMYSQ DSIDLLQNSG
LQFKKHEEEG IDTLYFAELL MTSGLVLCEN VKWLSFHSGY DFGYLVKLLT DARLPEEEHD
FFQILNLFFP AIYDVKYLMK SCKNLKGGLQ EVADQLELKR IGRQHQAGSD SLLTGMAFFR
MKELFFEDNI DDAKYCGRLY GLGSGTSQTQ NGLATTNQDD PNNKH
//
