ID   A0A3B4AD21_9GOBI        Unreviewed;      1539 AA.
AC   A0A3B4AD21;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPMGP00000014953.1};
OS   Periophthalmus magnuspinnatus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX   NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000014953.1, ECO:0000313|Proteomes:UP000261520};
RN   [1] {ECO:0000313|Ensembl:ENSPMGP00000014953.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   STRING; 409849.ENSPMGP00000014953; -.
DR   Ensembl; ENSPMGT00000015939.1; ENSPMGP00000014953.1; ENSPMGG00000012248.1.
DR   Proteomes; UP000261520; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0051262; P:protein tetramerization; IEA:InterPro.
DR   Gene3D; 1.20.5.1010; TRPM, tetramerisation domain; 1.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR041491; TRPM_SLOG.
DR   InterPro; IPR032415; TRPM_tetra.
DR   InterPro; IPR037162; TRPM_tetra_sf.
DR   PANTHER; PTHR13800:SF7; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 3; 1.
DR   PANTHER; PTHR13800; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF18139; LSDAT_euk; 1.
DR   Pfam; PF16519; TRPM_tetra; 1.
PE   4: Predicted;
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00023303}.
FT   TRANSMEM        724..742
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        799..818
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        866..884
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        896..914
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        935..955
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1013..1038
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          82..347
FT                   /note="TRPM SLOG"
FT                   /evidence="ECO:0000259|Pfam:PF18139"
FT   DOMAIN          808..1047
FT                   /note="Ion transport"
FT                   /evidence="ECO:0000259|Pfam:PF00520"
FT   DOMAIN          1139..1193
FT                   /note="TRPM tetramerisation"
FT                   /evidence="ECO:0000259|Pfam:PF16519"
FT   REGION          1508..1539
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1539 AA;  173419 MW;  603B27D591BACA41 CRC64;
     MSQSDLDLKV ASLSSRCCCG RLIGQHVGLP PGISSSQNDK AERLAKNDSL SEKWSISKHT
     QLSPTDAFGT IEFQGGGHSN KAMYVRVSYD TKPDLLLHLM TKEWQLDLPK LLISVHGGLQ
     NFELQPKLKQ VFGKGLIKAA MTTGAWIFTG GVNTGVIRHV GDALKDHASK SRGKICTIGI
     APWGIVENQE DLVGKDVVRP YQTMSNPMSK LTVLNSLHSH FILADNGTTG KYGAEVKLRR
     QLEKHISLQK INTRIGQGVP VVALIVEGGP NVISIVLEYL RDTPPVPVVV CDGSGRASDI
     LAFGHKYSEE GGIINESLRD QLLVTIQKTF TYSRTQAQHL FIILMECMKK KELITVFRMG
     SEGHQDIDLA ILTALLKGAN ASAPDQLSLA LAWNRVDIAR SQIFIYGQQW PVRNTSCYTE
     VTLFTVFLIV FIQVGSLEQA MLDALVLDRV DFVKLLIENG VSMHRFLTLS RLEELYNTRH
     GPSNTLYHLV RDVKKGNLPP DYRISLIDIG LVIEYLMGGA YRCNYTRKRF RTLYHNLFGP
     KRPKALKLLG MEDDMPIRRG RQKTTRKREE EVDIDLDDPE INHFPFPFHE LMVWAVLMKR
     QKMALFFWQH GEEAMAKALV ACKLCKAMAH EASENDMVDD ISQELNHNSR EFGQLAVELL
     DQSYKQDEQM AMKLLTYELK NWSNATCLQL AVAAKHRDFI AHTCSQMLLT DMWMGRLRMR
     KNSGLKVILG LLLPPSILSL EFKNKDEMSY MPQEQEAMLG KVSTETARKK DVEEVQSRHR
     LIPMGRKIYE FYNAPIVKFW FHTLAYVGYL MLFNYIVLVK MDLWPSPQEW IVIAYIFTNG
     IEKMREILMS EPGKLLQKVK VWLQEYWNIT DLMAILIFSV GMVLRLQEPP LMSYGRVIYC
     VNIIYWYIRL LDIFGVNKYL GPYVMMIGKM MIDMMYFVII MLVVLMSFGV ARQAILNPNE
     DASWMLARNI FFMPYWMIYG EVFADEIDPP CGQNVTTGDG AVVTLPPCKT GAWIVPAIMA
     CYLLVANILL VNLLIAVFNN TFFEVKSISN QVWKFQRYQL IMTFHERPVL PPPLIIFSHI
     TMVLKHLCCR WRKHDDDERD YGLKLFITED ELKKVHDFEE QCIEEYFREK DDHFHSSNDE
     RIRVTSERLE NMAMRLEEVN EREHFMKASL QTVDIRLAQM EELIGRITVA LERVTGVERG
     EVNKARSRTS SDCTDSAYML RQGDSFNSTE GNAYRLPEEL EGAALGSMSP PSPTTIASRV
     RSHSFYVGGS RGGERPSGAE RAESFFKERS LSLHRANSSQ SVSSAAAPKE SKPLPLATLA
     VSQQHRPSSC IDIYVSTSEE VGPAEVFLDP LRVVPPLYRG LSLQSDTVEM VLPGGRDFSS
     ATTSGLGDRP SEGGTGCTGT GIMYDDSAAA DLSLCSAHLL PDTSLPPWDT EPSPPPSAGL
     LERSKSSRYL STVGTSFLEE PPLVKSHSLM FTPRGCYGGL GPGIQVKAAE YTSITDCIDT
     RCVSTPYTPV ERSNSPGAPI QRERPNSATQ SQTLRILMS
//