ID   A0A3B4AIB6_9GOBI        Unreviewed;       543 AA.
AC   A0A3B4AIB6;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=SEFIR domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Periophthalmus magnuspinnatus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX   NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000016852.1, ECO:0000313|Proteomes:UP000261520};
RN   [1] {ECO:0000313|Ensembl:ENSPMGP00000016852.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR   AlphaFoldDB; A0A3B4AIB6; -.
DR   STRING; 409849.ENSPMGP00000016852; -.
DR   Ensembl; ENSPMGT00000017995.1; ENSPMGP00000016852.1; ENSPMGG00000013824.1.
DR   Proteomes; UP000261520; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030368; F:interleukin-17 receptor activity; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.11530; -; 1.
DR   InterPro; IPR039465; IL-17_rcpt-like.
DR   InterPro; IPR027841; IL-17_rcpt_C/E_N.
DR   InterPro; IPR013568; SEFIR_dom.
DR   PANTHER; PTHR15583; INTERLEUKIN-17 RECEPTOR; 1.
DR   PANTHER; PTHR15583:SF5; INTERLEUKIN-17 RECEPTOR E; 1.
DR   Pfam; PF15037; IL17_R_N; 1.
DR   Pfam; PF08357; SEFIR; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Inflammatory response {ECO:0000256|ARBA:ARBA00023198};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        221..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          36..203
FT                   /note="Interleukin-17 receptor C/E N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF15037"
FT   DOMAIN          258..459
FT                   /note="SEFIR"
FT                   /evidence="ECO:0000259|Pfam:PF08357"
FT   REGION          501..543
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        505..533
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   543 AA;  60977 MW;  6FC16F928F4E782A CRC64;
     NESLKSVTVY VEPGPKVSAR PLYKRSISPY SDADVNDIWR STKFKLESNV LAMVLKCPTS
     ETEMSTALCW KHNGYCTVVI TLSNCMNFIF VQEYNISAVD KHPQMCLLWS LNGSQNITCH
     FKSGMSSWMV NTELMRQGIF VYINSTVPAK FSAQLCKLNQ TTCASMGQIH SLNTVRIYMR
     VATFHLSVLS AEERPCVQVW QSEPVLYGKR IMCFDYTRTR YGLYVAMAIV CVVIMIVLGV
     CFHWLTKKGT AGWLHVPRPI LLVCSSEDSV HVSTACALAS ILQGDLGAIV HLALWAQSVQ
     SQCGMRVADV GPLPWLYGQW DTVIEAQGII LIMWSLDAKI AYKKWCSEKK SIKSSHQKDF
     ISHRPHKTEN SPILTEKCKF KVESHAAQRP DVSKPCTVIA PVFKAALTCL MGMLQENKPQ
     KVVFVSLHGH NNSKDIPKAF RGIPRFCLPH QFSGLIQELG VQTRLSENSR FHCWPRLLSK
     VLCFWLAKQL AKRLQTHRRF SSRRTVRSSA SAPHHLTSAS PQPHLSLTSA SPPGSRFRGK
     GIS
//