ID   A0A3B4AIJ1_9GOBI        Unreviewed;       893 AA.
AC   A0A3B4AIJ1;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPMGP00000016913.1};
OS   Periophthalmus magnuspinnatus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX   NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000016913.1, ECO:0000313|Proteomes:UP000261520};
RN   [1] {ECO:0000313|Ensembl:ENSPMGP00000016913.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B4AIJ1; -.
DR   STRING; 409849.ENSPMGP00000016913; -.
DR   Ensembl; ENSPMGT00000018057.1; ENSPMGP00000016913.1; ENSPMGG00000013861.1.
DR   Proteomes; UP000261520; Unplaced.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   CDD; cd01221; PH_ephexin; 1.
DR   CDD; cd00160; RhoGEF; 1.
DR   CDD; cd11938; SH3_ARHGEF16_26; 1.
DR   Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR035797; ARHGEF16/ARHGEF26_SH3.
DR   InterPro; IPR035899; DBL_dom_sf.
DR   InterPro; IPR000219; DH-domain.
DR   InterPro; IPR047271; Ephexin-like.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR047270; PH_ephexin.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR12845; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR   PANTHER; PTHR12845:SF4; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 26; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00621; RhoGEF; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00325; RhoGEF; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS50010; DH_2; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   4: Predicted;
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          462..646
FT                   /note="DH"
FT                   /evidence="ECO:0000259|PROSITE:PS50010"
FT   DOMAIN          688..805
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          812..872
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          120..140
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          157..261
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          364..390
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          405..458
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        364..384
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        405..419
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        427..443
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   893 AA;  100528 MW;  839B029876E327BB CRC64;
     MDYGNDVDLS NNNITPLWRR RSDNCRSPQI SRNAKPRPVS YHINGVMTTD FPVEDKCSFT
     LSQPDERILV TPTPNTAVLK HVLNKPTKKN RVVRSISIGH FSNGRFSLPK FRSEDNRSAS
     LDNRICNGGS DKGKYNNGMT VWPEKKRLSG QLSLNSQKEA LRTSDIHSSL SPPQTPNGNS
     YEELSSSSSN CSPLCRTPTP SHSSTSSIPS LSSLNSSDPP TPRSSSPDRT QSKCSVSESR
     HSSSSSTSPS ISPSPHIVLS TNSPAARKMG TQQIIPKGLA SALLGLDNAK RSTKALSMVE
     TGAYFSTGVQ KQEEGDGDSP GTLRRGLRST SYRKAVVSGV DEVDNVFLEA KSLQLSPAVV
     KGLNREKTSS PTSPLSPEKK NVLTSQRTFD SEEEELYQNY QEKALHNDSD EDADSREPKP
     DNNIVVQYKP LRTSWSQLSD PPPPHTHTHI GLSERLSQEE RKRQEAIFEV ISSEHSYLHS
     LEILIRMFKN STELSEAMTK TEHHHLFSNI TDVCEASKKF FSELEERHQQ SIVIHDISDI
     VCKHAQSNFD PYITYCSNEV YQQRTLQRLV SKNPAFKEVL TRIESHPDCR NLPMISFLIL
     PMQRITRLPL LMDTICHKTL KDSAEYEKCK KALQAVSKVV RKCNEGARTM ERTEMMYTIN
     SQLEFKIKPF PLVSSSRWMV KRGELTAFVE DSGIFLKRTS RQQVYFFLFN DVLIVTKKKS
     EESYTVIDYA LRDEIWVGSC QPEDVSLSPV RSAPSMLSSK QGSTNHLFRL TFRSNHSGEK
     VLMILGTDSL NERARWISAL GQSVNNKKSL DRNAMQVEAI RTYTAKQPDE LSLQVADVVL
     ISQTVDGWYE GERLRDGERG WFLLECTQPI TCQATIERNM QRMDRLQGLE TNV
//