ID A0A3B4AJ73_9GOBI Unreviewed; 390 AA.
AC A0A3B4AJ73;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=TNFR-Cys domain-containing protein {ECO:0000259|PROSITE:PS50050};
OS Periophthalmus magnuspinnatus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000017158.1, ECO:0000313|Proteomes:UP000261520};
RN [1] {ECO:0000313|Ensembl:ENSPMGP00000017158.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR AlphaFoldDB; A0A3B4AJ73; -.
DR STRING; 409849.ENSPMGP00000017158; -.
DR Ensembl; ENSPMGT00000018318.1; ENSPMGP00000017158.1; ENSPMGG00000014052.1.
DR Proteomes; UP000261520; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR CDD; cd13416; TNFRSF16; 1.
DR Gene3D; 6.10.250.1780; -; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 3.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR041448; TNFR16_TM.
DR InterPro; IPR022325; TNFR_16.
DR InterPro; IPR034046; TNFRSF16_N.
DR PANTHER; PTHR46605; TUMOR NECROSIS FACTOR RECEPTOR; 1.
DR PANTHER; PTHR46605:SF3; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16; 1.
DR Pfam; PF18422; TNFR_16_TM; 1.
DR Pfam; PF00020; TNFR_c6; 3.
DR PRINTS; PR01966; TNFACTORR16.
DR SMART; SM00208; TNFR; 4.
DR SUPFAM; SSF57586; TNF receptor-like; 3.
DR PROSITE; PS00652; TNFR_NGFR_1; 2.
DR PROSITE; PS50050; TNFR_NGFR_2; 4.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 232..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..50
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 17..50
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 52..93
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 52..93
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT REPEAT 94..132
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 94..132
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT DOMAIN 134..175
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 134..175
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT REGION 266..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 266..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 30..43
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 72..85
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 75..93
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 111..124
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 114..132
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 135..150
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 390 AA; 42614 MW; E49BE3E2B5AC6FE9 CRC64;
SSRGRHRFQY GRALFSSCDS GQYTDDGECC KECPPGEGVV QKCGAAQTVC AQCLDSETYS
ENYSHTETCL PCTQCVGMMR METPCTDSND AICVCNYNFF LSDITGQCEP CTVCPMGQGV
LEHCTHNHDT MCEECVDDTF SERDSSLDPC LPCTICDEDT EIQLEECTPI SDSVCHNPLL
PTYVPLTDTT MPLLSTSLFF PDGSESPLPG ETTTSSSGSP RFLGGGLNEN LIPIYCSILA
AVVVGFIAYI VFKRWNSCKQ NKQAANNRAA TNNQMVTPEG EKLHSDSGIS VDSQSLQEQQ
QQQQQQQQQQ QAQAEVQSQP THAPDTSWIE IKSDILDTTG IQLRGEGGLS LCIQTLRDIS
SAKGMCKAAV TGTRSTLVLM VLLLFWQRVS
//
