ID A0A3B4AQ74_9GOBI Unreviewed; 667 AA.
AC A0A3B4AQ74;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPMGP00000019283.1};
OS Periophthalmus magnuspinnatus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000019283.1, ECO:0000313|Proteomes:UP000261520};
RN [1] {ECO:0000313|Ensembl:ENSPMGP00000019283.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B4AQ74; -.
DR STRING; 409849.ENSPMGP00000019283; -.
DR Ensembl; ENSPMGT00000020557.1; ENSPMGP00000019283.1; ENSPMGG00000015663.1.
DR Proteomes; UP000261520; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR22834; NUCLEAR FUSION PROTEIN FUS2; 1.
DR PANTHER; PTHR22834:SF9; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 37; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50002; SH3; 2.
PE 4: Predicted;
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 24..211
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 255..453
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 492..555
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 595..659
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 553..594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 667 AA; 76238 MW; 47A387190C53987C CRC64;
LKEQSEEVQR KSEEEKSQEI QAQRQNLAIQ ELLESERNYL RMLQLSSGFI RENLLKIQPP
LVNVDCLFEH LPEVVSVTSR LLDSVDQDQL QPGDPNFLQN FCNAFLSLSS DMEMAYKEYL
SNYNQVTTWE VNCKQKEALW DQVVKVLKSS APELKASSLS FFLVMPVQRI ARYPLLLQTI
LKHTDPSHPA YALLEKTAHT SVNINCRINE YKRIREFREV ANKYKKTETL SIKDMINRLN
THSIFKKTAR LSQQIKHETG IVPKLVDEEF DALEGFFYLL EKCILELLEN VETYLSHLQA
FLSYKTEEFD LYMDAQREAV CYKEITTALR QWILPTFEKR LRALIHKPLC ALRDLLVGPR
NLIRKRLDKL LDYELIEAKS NLSYEEQAAA NTYKTMNTLL LTELPRFNTV SLQLIWRLLG
TFSCLHRDLA SDMTQLFQTF ATQLPHSGMS SSTFWDWAEA AVMEGMRKLQ DLCQTVEEAL
SAPVSMLCQK HPQERIFEAT CGVVGSRDLD LSLIKGELVA VVSERDSKGD RRRWLVDAGG
KRGYAPASKL RQYQAPPAEG PPPPSPQPNR ADTKLEGRHL SKSLDRRPSP LSLSPLSPSV
VAAYPFTARG HREVSLGAGE PVRVLEPHDK KGNPEWSLVQ TQGGQSGYVP SNYLTTVPQM
SYLRPYP
//
