ID A0A3B4AQR2_9GOBI Unreviewed; 990 AA.
AC A0A3B4AQR2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPMGP00000019040.1};
OS Periophthalmus magnuspinnatus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000019040.1, ECO:0000313|Proteomes:UP000261520};
RN [1] {ECO:0000313|Ensembl:ENSPMGP00000019040.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the formin homology family.
CC {ECO:0000256|ARBA:ARBA00023449}.
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DR AlphaFoldDB; A0A3B4AQR2; -.
DR STRING; 409849.ENSPMGP00000019040; -.
DR Ensembl; ENSPMGT00000020303.1; ENSPMGP00000019040.1; ENSPMGG00000015496.1.
DR Proteomes; UP000261520; Unplaced.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR GO; GO:0022604; P:regulation of cell morphogenesis; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR043592; FMNL_animal.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR PANTHER; PTHR45857; FORMIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR45857:SF3; FORMIN-LIKE PROTEIN 3; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF06371; Drf_GBD; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 11..396
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 500..890
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 450..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 325..352
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 861..916
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 462..482
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 990 AA; 113410 MW; 160E3763BB2C6927 CRC64;
MFVLLNYSYK PPLLWLLLPQ IYFHVFQNSM NLPPDKARLL RQYDNEKKWD LICDQERFQV
KNPPHTYIQK LRGYLDPGVT RKKFRRRVQE STKVLRELEI SLRTNHIGWV REFLNDENRG
LDILVEYLSF AQCAVIYGSV SNSKTIKNSR LVSQKDDVHV CIMCLRAIMN YQYGFNMVMS
HAHAVNEIAL SLNNKNSRTK ALVLELLAAV CLVRGGHEII LSAFDNFKEV CKEKHRFERL
MDYFRGEEGN IDFMVACMQF INIVVHSVED MNFRVHLQFE FTKLGLDDYL EKCKHTESDK
LSVQIQAYLD NVFDVGGLLE DAETKNAALE KVEELEEHLS HVTEKLLEVE NETMMKVADL
EKVLILKDKE LQAVRETYEF TNTQVTTLRR VIKEKDAAFQ RHFNIERRLL ELEQQGTIRL
HKKPDGDISI EPLGVGPAAI PLGNIGQLSL GSTLPHTEPG GPDLRPCAPI PPPPPPPLAP
PLPGTSPSVI FSTGLSAIKI KKPIKTKFRL PVFNWTALKP NQINGTVFNE IDDERVLEEL
DLEKFEELFK TRAQGPVVDL SCTKSKVAQK AQNKVTLLDA NRSKNLAITL RKANKTTEEI
CKAIEKFDLK ALPVDFVECL MRFLPTEGEV KVLRQYERER RPLDQLADED RFMLLFSKIE
RLTQRMNIIT FVGNFADNIN MLTPQLNAII AASGSVKSSP KLKRMLEIIL ALGNYMNSSK
RGSVYGFKLQ SLDLLLDTKS TDRKMTLLHY IALIVKEKYP ELANFYNELH FVDKAAAVSL
ENVLLDVREL GKGMDLIRRE CSLHDHSVLK GFLQASDTQL DKLQRDAKTA EEAFNNVVNY
FGESAKTTPP SVFFPVFVRF IKAYKDAVEE NEQKKKQEQA MREKLLAQEA KEQDPKVQAQ
KKRHQQQELI AELRRRQAKD HRPVYEGKDG TIEDIITGGT SRTLNRPYVA NKSPSRRRSK
MTVVIHCSAP LQCTLCYVVQ TPAHLEHSNH
//
