ID A0A3B4AVY0_9GOBI Unreviewed; 2561 AA.
AC A0A3B4AVY0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000259|PROSITE:PS50021};
OS Periophthalmus magnuspinnatus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000020734.1, ECO:0000313|Proteomes:UP000261520};
RN [1] {ECO:0000313|Ensembl:ENSPMGP00000020734.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the filamin family.
CC {ECO:0000256|ARBA:ARBA00009238}.
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DR STRING; 409849.ENSPMGP00000020734; -.
DR Ensembl; ENSPMGT00000022105.1; ENSPMGP00000020734.1; ENSPMGG00000016786.1.
DR Proteomes; UP000261520; Unplaced.
DR GO; GO:0043232; C:intracellular non-membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR CDD; cd21310; CH_FLNC_rpt1; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 24.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR044801; Filamin.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR001298; Filamin/ABP280_rpt.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR38537; JITTERBUG, ISOFORM N; 1.
DR PANTHER; PTHR38537:SF17; JITTERBUG, ISOFORM N; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00630; Filamin; 24.
DR SMART; SM00033; CH; 2.
DR SMART; SM00557; IG_FLMN; 24.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF81296; E set domains; 24.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50194; FILAMIN_REPEAT; 24.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 16..122
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 139..242
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REPEAT 250..347
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 349..447
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 448..544
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 545..637
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 640..728
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 729..831
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 832..930
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 931..1026
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1027..1119
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1120..1214
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1215..1314
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1315..1407
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1408..1503
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1504..1600
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1601..1696
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1719..1788
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1788..1880
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1878..1966
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1969..2061
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2059..2158
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2161..2253
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2255..2348
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2352..2444
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2466..2560
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
SQ SEQUENCE 2561 AA; 274946 MW; DA2D584FBDF81179 CRC64;
MPATEKDLAE DAPWKKIQQN TFTRWCNEHL KCLNKRINDL QKDLSDGLKL IGLLEVLSQK
KMYRKYHARP NFRQMKLENV SVALEFLERE HIKLVSIDSK AIVDGNLKLI LGLIWTLILH
YSISMPMWDD EDDEDAKKLT PKQRLLGWIQ NKVPQLPITN FHRDWRDGKA LGALVDNCAP
GLCPDWETWD PSQPVENARE AMQQADDWLG VPQVIAPEEI VDPNVDEHSV MTYLSQFPKS
KLKPGAPLKA KTLHPKRAKA YGPGIEPLGN MVLKPAEFLV ETVEAGLGEV IVYVEDPEGH
TEEVIIPNND KSRSYSVVYL PKVEGLHKVK VLFAGQDIDR SPFMVTVSKA MGDPTRVQAR
GPGLQPAGNV ANKPTYFDIY TAGAGAGDVG VIIVDSNARR DTVEIVLENK GDSIFRCTYV
PVLEGAHTVY VTFAGQQIPK SPYTVHISEA CNPNACRASG RGLQPKGVRV KEVADFKVYT
KGAGSGELNV TVKGPKGLDE PVKVLELENG LYECNYYPVN TGKYIVTITW GGHSIPRSPF
EVHVSEEAGP QKVRAWGPGL ETGMVGKSAD FVVEAIGMEV GTLGFSIEGP SQAKIECDDK
GDGSCDVRYW PTEAGDYAVH VICDDEDIKD SPFMAHILPI NCYGPGLEPI GCIVNKPADF
TIDTHGAGGG ELKLYAQDAE GFPIDIQITD NGDGTYFCVY IPTKPIKHTI IITWGEVNVP
RSPFRVTIGE GSHPENVKVY GPGVEQFGLK SNEPTYFTVD CSEAGQGDVS IGIKCAPGVV
GPIEADIDFD IIKNDNDTFT VKYIPPGPGQ YTIMVLFADQ EIPVSPFRIK VEPSHDAAKV
RAEGPGLNKT GVEVGKPTHF NIYTKGAGKA TPEVYFSGTV KSEAVRDFEI IDNHDYSYTV
RYTAIQQGNM SITVCHGGDP IPKSPFNITV APPLDLNKVK VQGLNNKVDV GKDQEFTVCT
RGAGGQGKLD VKITSPSRRP IPCKLESGTS NEMYTINYIP PEEGTYRVDI SYDGNPIPGS
PFPVEGVMPP DPSKVRAYGP GLEGGVVGKP APFAIDTKGA GTGGLGLTVE GPCEAKIECQ
DNGDGSCSVS YLPTEPGEYS INILFADQHI PGSPFKATVL PAFDPSKVTA SGPGLERGKV
NEDGFFTVDC SKAGDAELTI EIISDSGAKA EVHVQNNSDG TYSITYIPQF QGMYTITIKY
GGQSVPNFPT RLQVDPAVDT SGVMVYGPGV EPRGLLKEVT THFTVDARVN CKTGGNHIKV
GISNPSGITT DAFITDKGDG TYRVEYTPYE DGLHLIEVLY DDVPVPNSLF RVVVTEGCDP
SRVRAYGPGL EEGLVNKPNR FTVETRGAGT GGLGLAIEGP SEAKMSCKDN KDGSCSVEYI
PFTPGEYDVN ITFGGLPIPG SPFRVPVREV VDPSKVRCSG PGLGNGVRAQ VPQTFTVDTS
KAGMAPLEVL LYGPTGLTEP VSITDNGDGT YTVNYTPALD GPYSVCVKYA DQEVPRSPFK
IKTLPAHDAS KVRASGPGLN SSGVPASLPV EFTIDARDAG EGLLTVQILD PEGKPKKANI
RDNRDGTYTV FYVPDMTGRY TITIKYGGDE IPYSPYRIHA IPSGDASKCL VTGSGVSPTI
QIGEETVITV DAKAAGKGKV TCKVSTPDGA ELDVDVVENA DGTFDIYYTA PEPGKYVITI
RFGGEHIPNS PFHVVVSLST ATDDPASVVD GMDAVLRPFS LVIPFTVQKG EITGVVRMPS
GRTACPYITD NKDGTVTVKY SPTERGLHEM DIKYDGNHIP GSPLQFYVDA INSGHVTAYG
PGLSHGMVNR PAAFTIVTKD AGEGGLSLAV EGPSKAEISC KDNKDGTCTV SYLPTAPGDY
NIIVKFDDKH IPGSPFTAKI TDDSMRMSQL NVGTATDVSL KITETDLSSL TTSIRAPSGN
EEPCLLKRLP NRHIGISFTP KEVGEHVVSV KKNGKHVTNS PFKIMVGQSE IGDASKVKVY
GQGLVEGHTL EMAEFIVDTR NAGYGGLGLS IEGPSKVDIN CEDVEDGTCK VTYCPTEPGN
YIINIKFADQ HVPGSPFTVK VFGEGRMKES ITRRRQAPSI ATVGSTCDLN LKIPGEVANQ
EMTAQVTSPS GKTEEAEIIR GEDSTYSVRF IPQEMGPHTV SVKYRGQHVP GSPFQFTVGP
LGEGGAHKVR AGGTGLDRGV AGIPAEFSIW TREAGAGGLS IAVEGPSKAE ITFEDRKDGS
CGVSYVVQEP GDYEVSIKFN DEHIPDSPFI VPVATLSDDA RRLTVTSLQE MGLVVGQEAS
FAVQLNGVRG LVDAKIHTPS GAIEECYITE LDKDQYAIRF VPRENGVHSI DVRFNGSHIP
GSPFKIRVGD LGQVGDPGMV SAFGAGLEGG ITGVAAEFVV NTCNAGAGAL SVTIDGPSKV
KMDCQECPEG YKVFYTPMAP GSYLISIKYG GPQHIVGSPF KAKVTVLVET VSKSSTVGGA
FSSLPKFSSD ASKVTSRGAG LSKAFVGQKN AFTVDCSKAG TNMLMVGVHG PKTPCEEVYV
KHMGNRMYNV TYTVKEQGSY ILIVKWGDEH IPGSPFHVTV P
//
