ID A0A3B4B0J2_9GOBI Unreviewed; 1367 AA.
AC A0A3B4B0J2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Laminin, alpha 4 {ECO:0008006|Google:ProtNLM};
OS Periophthalmus magnuspinnatus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000023057.1, ECO:0000313|Proteomes:UP000261520};
RN [1] {ECO:0000313|Ensembl:ENSPMGP00000023057.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR Ensembl; ENSPMGT00000024564.1; ENSPMGP00000023057.1; ENSPMGG00000006952.1.
DR Proteomes; UP000261520; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProt.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd00055; EGF_Lam; 3.
DR CDD; cd00110; LamG; 5.
DR Gene3D; 2.60.120.200; -; 5.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR010307; Laminin_dom_II.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR15036:SF47; LAMININ SUBUNIT ALPHA-4; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00053; Laminin_EGF; 3.
DR Pfam; PF00054; Laminin_G_1; 1.
DR Pfam; PF02210; Laminin_G_2; 4.
DR Pfam; PF06009; Laminin_II; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00180; EGF_Lam; 3.
DR SMART; SM00282; LamG; 5.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 5.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS50027; EGF_LAM_2; 2.
DR PROSITE; PS50025; LAM_G_DOMAIN; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460}.
FT DOMAIN 84..138
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 139..192
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 423..622
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 634..814
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 821..989
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1040..1220
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1227..1367
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 915..939
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 989..1032
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 915..929
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 109..118
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 164..173
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 176..190
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 1367 AA; 151261 MW; FB193C7B3850970E CRC64;
MVYYNTDVIL PGADTAKVCG KGFFLSERGL CLPCNCKGNA DHCQDITGVC INCKNHSTGD
FCEHCEDGFL LGAGPNGRRS CQPCACPLAC LSSFAVHCDR GTGSLRCKCQ EGYAGHSCER
CAPGYYGNPM VIGSSCKRCD CSGNSDPNLI FNECHNVTGH CQHCWGNTAG ANCERCAPGF
YGDAITAKNC RECECESGHC DMHTGECLLE AAISLCNSCD ECTWSLIGDL RISNKTLDQL
KVAVLNISTG AAANDRIKYY NYTALRLQVV TPHTLLFQQA GSVDTLCIFE TTNTGFVSDL
CCSDLRESDA NGFVQRAISA ANVYNNIIKY IHDANITSRT TFNLSQKAQE VFLPVRLWDA
VIYSVKSNHY AYVAVENLNI LVPELLDKLR VVEQKKPVNN VTTNILRIRE LIAQARSVAK
KVQVSMKFSG QSAVEVHPHT NLDDLKTVTS ISLFIRVDPD KDPIEDRFIL YLGDRNGRKD
YMGLAIKNDN LVYVYNLGGE DVEIPLGSKP VSQWPAVFNY VKVERLGRHG KVFLTIPSQS
SSDEQKFIQK GQAPGTDSLF DIDPNDIVFF VGGVPAGVKL PPPLSLAPFV GCIELESINN
DVISLYNFKE THQMDMVAST PCPRYKLAFS QSRIASYLFD GTGYALINDI ERRGKFGVVT
RFDISVRTVA NDGVLLLMVN GLKFFLLELK NGYLRLIYDF GFSGGPNRLE EKLPVLQIND
AKYHEVSVIY HQSKKVILLV DKGHVKSIEN PKTTLPFSHV YIGGAPSNVL KISVYRTELA
TVVGLKGCVK GFQFQKKDFN LLEEPGTIGI SSGCPEESFM SRKAYFIGES YLGSTAKTSP
FDSFEGGMNF RTLQPSGLLF YHREGSDEFS IALENGGVIL NNRGTKVKSH KKQYSDGRTH
FLVASINNQR YSLMIDDKDK QEKKRPPSAS RTSSDSTLKN FYFGGSPHSS LKNFTGCISY
AYISRLERDI EPEDFQRYPE KVKVSLQECP VRRPPAALQS QNPRGTRGEH SKKHNSDDPN
TEGGSCSQSP ISRAPQRTFH YGGFSHSRHH YSLPQHALDH RYEWSFCVHR WHLSLSLRTI
SSFGLMVYVC DMEERSFMAL YLAHGRLELT FSAGGDPVTI SSQNKYNDGK WHNVDLIGDG
NLGRLIIDGL TLLETRAPKD RGTNSSSQLQ GPLYVGGVPP GKAQRNVPTS SLHSIPGCLR
NLQLDGEWLP APDSFGVVPC FSGSFEEGTY FSTKGGHVLL DDSFHLGLRF ELQMEVRPRV
DSGLLLHVRT VEGYFSLFLH QAIVLVNDGT HEFFTKVVPK HSLCTGTWHR ITVIRKANVV
QLAVDLEVNH VVGPQGPNVN YIGPVWIGGA PSKTIHVHTS FSLATVL
//
