ID A0A3B4B0Y4_9GOBI Unreviewed; 1452 AA.
AC A0A3B4B0Y4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Laminin, alpha 4 {ECO:0008006|Google:ProtNLM};
OS Periophthalmus magnuspinnatus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000022261.1, ECO:0000313|Proteomes:UP000261520};
RN [1] {ECO:0000313|Ensembl:ENSPMGP00000022261.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR Ensembl; ENSPMGT00000023708.1; ENSPMGP00000022261.1; ENSPMGG00000006952.1.
DR Proteomes; UP000261520; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProt.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd00055; EGF_Lam; 3.
DR CDD; cd00110; LamG; 5.
DR Gene3D; 2.60.120.200; -; 5.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR010307; Laminin_dom_II.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR15036:SF47; LAMININ SUBUNIT ALPHA-4; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00053; Laminin_EGF; 3.
DR Pfam; PF00054; Laminin_G_1; 1.
DR Pfam; PF02210; Laminin_G_2; 4.
DR Pfam; PF06009; Laminin_II; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00180; EGF_Lam; 3.
DR SMART; SM00282; LamG; 5.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 5.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS50027; EGF_LAM_2; 2.
DR PROSITE; PS50025; LAM_G_DOMAIN; 5.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460}.
FT DOMAIN 92..146
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 147..200
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 502..701
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 713..890
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 897..1065
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1096..1274
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1281..1449
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 992..1015
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1065..1110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 296..345
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1096..1110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 117..126
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 172..181
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 184..198
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 1452 AA; 159945 MW; 0659FCF1C9C20CDF CRC64;
REEHIQSTMV PQLQELEDSS RFIVQVCGKG FFLSERGLCL PCNCKGNADH CQDITGVCIN
CKNHSTGDFC EHCEDGFLLG AGPNGRRSCQ PCACPLACLS SFAVHCDRGT GSLRCKCQEG
YAGHSCERCA PGYYGNPMVI GSSCKRCDCS GNSDPNLIFN ECHNVTGHCQ HCWGNTAGAN
CERCAPGFYG DAITAKNCRE CECESGHCDM HTGECLLEAA ISLCNSSCDE CTWSLIGDLR
ISNKTLDQLK VAVLNISTGA AANDRIKYYN YTALRLQVVT PHTLLFQQAG SYHAAIDGAG
QKLQDKSEQL AQVDAELVLR ASEHAEMLDT RANALEDDLR ESDANGFVQR AISAANVYNN
IIKYIHDANI TSRTTFNLSQ KAQEVCSVVK VLFLSRQDTS APELHSXXXN RSQDVLQTIT
PISNKVEQWA SNMKKKQYST EAYESAVNSA GEAVENLNIL VPELLDKLRV VEQKKPVNNV
TTNILRIREL IAQARSVAKK VQVSMKFSGQ SAVEVHPHTN LDDLKTVTSI SLFIRVDPDK
DPIEDRFILY LGDRNGRKDY MGLAIKNDNL VYVYNLGGED VEIPLGSKPV SQWPAVFNYV
KVERLGRHGK VFLTIPSQSS SDEQKFIQKG QAPGTDSLFD IDPNDIVFFV GGVPAGVKLP
PPLSLAPFVG CIELESINND VISLYNFKET HQMDMVASTP CPRYKLAFSQ SRIASYLFDG
TGYALINDIE RRGKFGVVTR FDISVRTVAN DGVLLLMVNG LKFFLLELKN GYLRLIYDFG
FSGGPNRLEE KLPVLQINDA KYHEVSVIYH QSKKVILLVD KGHVKSIENP KTTLPFSHVY
IGGAPSNISV YRTELATVVG LKGCVKGFQF QKKDFNLLEE PGTIGISSGC PEESFMSRKA
YFIGESYLGS TAKTSPFDSF EGGMNFRTLQ PSGLLFYHRE GSDEFSIALE NGGVILNNRG
TKVKSHKKQY SDGRTHFLVA SINNQRYSLM IDDKDKQEKK RPPSASRTSS DSTLKNFYFG
GSPHSSLKNF TGCISYAYIS RLERDIEPED FQRYPEKVKV SLQECPVRRP PAALQSQNPR
GTRGEHSKKH NSDDPNTEGG SCSQSPISRA PQRTFHYGGF SHSRWHLSLS LRTISSFGLM
VYVCDMEERS FMALYLAHGR LELTFSAGGD PVTISSQNKY NDGKWHNVDL IGDGNLGRLI
IDGLTLLETR APKDRGTNSS SQLQGPLYVG GVPPGKAQRN VPTSSLHSIP GCLRNLQLDG
EWLPAPDSFG VVPCFSGSFE EGTYFSTKGG HVLLDDSFHL GLRFELQMEV RPRVDSGLLL
HVRTVEGYFS LFLHQAIVLV NDGTHEFFTK VVPKHSLCTG TWHRITVIRK ANVVQLAVDL
EVNHVVGPQG PNVNYIGPVW IGGSELLLPD SVGPLKPYVG CMRGLSIDGR AVSLSKAALV
QGAVSARGCP AE
//
